AGP23_ARATH
ID AGP23_ARATH Reviewed; 61 AA.
AC Q8S2W4; Q9SVY3;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 12-DEC-2006, sequence version 2.
DT 25-MAY-2022, entry version 82.
DE RecName: Full=Arabinogalactan protein 23 {ECO:0000303|PubMed:12177459};
DE Short=AtAGP23 {ECO:0000303|PubMed:12177459};
DE AltName: Full=Arabinogalactan peptide 23 {ECO:0000303|PubMed:12177459};
DE Short=AG-peptide 23 {ECO:0000303|PubMed:12177459};
DE Flags: Precursor;
GN Name=AGP23 {ECO:0000303|PubMed:12177459}; OrderedLocusNames=At3g57690;
GN ORFNames=F15B8.120;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12177459; DOI=10.1104/pp.003459;
RA Schultz C.J., Rumsewicz M.P., Johnson K.L., Jones B.J., Gaspar Y.M.,
RA Bacic A.;
RT "Using genomic resources to guide research directions. The arabinogalactan
RT protein gene family as a test case.";
RL Plant Physiol. 129:1448-1463(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP PROTEIN SEQUENCE OF 23-35, HYDROXYLATION AT PRO-29; PRO-31 AND PRO-33,
RP GLYCOSYLATION AT PRO-29; PRO-31 AND PRO-33, AND GPI-ANCHOR AT SER-35.
RX PubMed=15322080; DOI=10.1074/jbc.m407594200;
RA Schultz C.J., Ferguson K.L., Lahnstein J., Bacic A.;
RT "Post-translational modifications of arabinogalactan-peptides of
RT Arabidopsis thaliana. Endoplasmic reticulum and
RT glycosylphosphatidylinositol-anchor signal cleavage sites and hydroxylation
RT of proline.";
RL J. Biol. Chem. 279:45503-45511(2004).
RN [6]
RP INDUCTION.
RX PubMed=25336567; DOI=10.1093/mp/ssu114;
RA Jia Q.S., Zhu J., Xu X.F., Lou Y., Zhang Z.L., Zhang Z.P., Yang Z.N.;
RT "Arabidopsis AT-hook protein TEK positively regulates the expression of
RT arabinogalactan proteins in controlling nexine layer formation in the
RT pollen wall.";
RL Mol. Plant 0:0-0(2014).
RN [7]
RP TISSUE SPECIFICITY.
RX PubMed=25053647; DOI=10.1093/jxb/eru300;
RA Pereira A.M., Masiero S., Nobre M.S., Costa M.L., Solis M.T.,
RA Testillano P.S., Sprunck S., Coimbra S.;
RT "Differential expression patterns of arabinogalactan proteins in
RT Arabidopsis thaliana reproductive tissues.";
RL J. Exp. Bot. 65:5459-5471(2014).
CC -!- FUNCTION: Proteoglycan that seems to be implicated in diverse
CC developmental roles such as differentiation, cell-cell recognition,
CC embryogenesis and programmed cell death. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC anchor {ECO:0000269|PubMed:15322080}.
CC -!- TISSUE SPECIFICITY: Expressed in pollen grains.
CC {ECO:0000269|PubMed:25053647}.
CC -!- INDUCTION: Up-regulated by AHL16/TEK. {ECO:0000269|PubMed:25336567}.
CC -!- PTM: Contains 4-hydroxyproline; hydroxylated on Pro-29, Pro-31 and Pro-
CC 33. {ECO:0000269|PubMed:15322080}.
CC -!- PTM: O-glycosylated on hydroxyprolines; noncontiguous hydroxylproline
CC residues are glycosylated with arabinogalactan.
CC {ECO:0000305|PubMed:15322080}.
CC -!- SIMILARITY: Belongs to the AG-peptide AGP family. {ECO:0000305}.
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DR EMBL; AF497624; AAM18712.1; -; mRNA.
DR EMBL; AL049660; CAB41186.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE79687.1; -; Genomic_DNA.
DR EMBL; BT028949; ABI49496.1; -; mRNA.
DR PIR; T06751; T06751.
DR RefSeq; NP_191328.1; NM_115629.4.
DR AlphaFoldDB; Q8S2W4; -.
DR STRING; 3702.AT3G57690.1; -.
DR PaxDb; Q8S2W4; -.
DR EnsemblPlants; AT3G57690.1; AT3G57690.1; AT3G57690.
DR GeneID; 824938; -.
DR Gramene; AT3G57690.1; AT3G57690.1; AT3G57690.
DR KEGG; ath:AT3G57690; -.
DR Araport; AT3G57690; -.
DR TAIR; locus:2076611; AT3G57690.
DR eggNOG; ENOG502S74N; Eukaryota.
DR HOGENOM; CLU_192501_1_0_1; -.
DR InParanoid; Q8S2W4; -.
DR OMA; MEMKQMA; -.
DR PRO; PR:Q8S2W4; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8S2W4; baseline and differential.
DR Genevisible; Q8S2W4; AT.
DR GO; GO:0031225; C:anchored component of membrane; TAS:TAIR.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR044702; AGP23/40.
DR PANTHER; PTHR34672; PTHR34672; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Direct protein sequencing; Glycoprotein; GPI-anchor;
KW Hydroxylation; Lipoprotein; Membrane; Proteoglycan; Reference proteome;
KW Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000269|PubMed:15322080"
FT PEPTIDE 23..35
FT /note="Arabinogalactan protein 23"
FT /evidence="ECO:0000269|PubMed:15322080"
FT /id="PRO_0000269027"
FT PROPEP 36..61
FT /note="Removed in mature form"
FT /evidence="ECO:0000305|PubMed:15322080"
FT /id="PRO_0000269028"
FT MOD_RES 29
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000269|PubMed:15322080"
FT MOD_RES 31
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000269|PubMed:15322080"
FT MOD_RES 33
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000269|PubMed:15322080"
FT LIPID 35
FT /note="GPI-anchor amidated serine"
FT /evidence="ECO:0000269|PubMed:15322080"
FT CARBOHYD 29
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000305|PubMed:15322080"
FT CARBOHYD 31
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000305|PubMed:15322080"
FT CARBOHYD 33
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000305|PubMed:15322080"
FT CONFLICT 38
FT /note="S -> L (in Ref. 1; AAM18712)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 61 AA; 5970 MW; 6657230285D0B762 CRC64;
MEMKKIACGV LFAAASMTAV MAAEEVGAPA PGPASAASAA LPALGSLVGA SLVSLFSYYL
H
