ERB1_PHANO
ID ERB1_PHANO Reviewed; 782 AA.
AC Q0UN56;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 3.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=Ribosome biogenesis protein ERB1 {ECO:0000255|HAMAP-Rule:MF_03027};
DE AltName: Full=Eukaryotic ribosome biogenesis protein 1 {ECO:0000255|HAMAP-Rule:MF_03027};
GN Name=ERB1 {ECO:0000255|HAMAP-Rule:MF_03027}; ORFNames=SNOG_06808;
OS Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS blotch fungus) (Parastagonospora nodorum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC Parastagonospora.
OX NCBI_TaxID=321614;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT analysis of the wheat pathogen Stagonospora nodorum.";
RL Plant Cell 19:3347-3368(2007).
CC -!- FUNCTION: Component of the NOP7 complex, which is required for
CC maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S
CC ribosome. {ECO:0000255|HAMAP-Rule:MF_03027}.
CC -!- SUBUNIT: Component of the NOP7 complex, composed of ERB1, NOP7 and
CC YTM1. The complex is held together by ERB1, which interacts with NOP7
CC via its N-terminal domain and with YTM1 via a high-affinity interaction
CC between the seven-bladed beta-propeller domains of the 2 proteins. The
CC NOP7 complex associates with the 66S pre-ribosome. {ECO:0000255|HAMAP-
CC Rule:MF_03027}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000255|HAMAP-
CC Rule:MF_03027}. Nucleus, nucleoplasm {ECO:0000255|HAMAP-Rule:MF_03027}.
CC -!- SIMILARITY: Belongs to the WD repeat BOP1/ERB1 family.
CC {ECO:0000255|HAMAP-Rule:MF_03027}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAT85459.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; CH445334; EAT85459.2; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_001797170.1; XM_001797118.1.
DR AlphaFoldDB; Q0UN56; -.
DR SMR; Q0UN56; -.
DR STRING; 13684.SNOT_06808; -.
DR GeneID; 5974060; -.
DR KEGG; pno:SNOG_06808; -.
DR eggNOG; KOG0650; Eukaryota.
DR InParanoid; Q0UN56; -.
DR OMA; MRPAKGE; -.
DR OrthoDB; 759498at2759; -.
DR Proteomes; UP000001055; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0070545; C:PeBoW complex; IBA:GO_Central.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR GO; GO:0043021; F:ribonucleoprotein complex binding; IBA:GO_Central.
DR GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR Gene3D; 2.130.10.10; -; 1.
DR HAMAP; MF_03027; BOP1; 1.
DR InterPro; IPR028598; BOP1/Erb1.
DR InterPro; IPR012953; BOP1_N_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR17605; PTHR17605; 1.
DR Pfam; PF08145; BOP1NT; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM01035; BOP1NT; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing;
KW WD repeat.
FT CHAIN 1..782
FT /note="Ribosome biogenesis protein ERB1"
FT /id="PRO_0000370437"
FT REPEAT 432..471
FT /note="WD 1"
FT REPEAT 475..516
FT /note="WD 2"
FT REPEAT 612..652
FT /note="WD 3"
FT REPEAT 653..692
FT /note="WD 4"
FT REPEAT 696..736
FT /note="WD 5"
FT REPEAT 752..782
FT /note="WD 6"
FT REGION 1..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 533..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..73
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 782 AA; 87899 MW; 3DD44C9E90DEC261 CRC64;
MSVNSRKRKV ATKAAPVQSS SDEELADGLL DGILSHSEDE SEDDQDAEDT DASSVIEGLS
DEDFEDEEDS GDEAEEIRKQ MRNLNTSGGS QQRKTRQPAH ERLDDGADGE LEGEEDESLK
PNYTVTTDAH GQVRYLYKEI DPVYESDDSD AEATNTIGNI PLTYYDEYPH IGYDINGKKI
MRPAKGEALD ALLDSIDIPK GWTGLTDPQT GKPLNLSEEE LDVLKRLTRN EVVEDGYDPY
PEMVAYFSGK QEIMPLSAAP EPKRRFIPSK HEAKRVMKIV KAIREGRIKP YKAPEEREED
EQISYDVWAD EKPRPEHSMH IPAPKLPPPG YEASYHPPPE YLPDKAEEEA WLQADEEDRE
KDFLPKNYEA LRKVPGYETF VKERFERSLD LYLAPRVRRN RLNIDPESLL PKLPDPEDLK
PFPTTCAAIF RGQEGRVRCV SVDPQGIFVA SGGDDGYVRI WELLTGRQVW NAKLSDEEAV
DAVQWRPTKD ASVLAAASGE HVYLIVPFTL LSPDVEQSSR DVLDAGWGYA TSKPSTAANG
EAPKQSPGKW SRPGSRMENK GILVQIEVRS AVKIINWHRR GDYFATVSPR GQSTAVAIHT
VSKHLTQLPF RRLKGIAQTA QFHPSKAIFF VATRNTIRSY DLAKQELVKI LQPGAKWISS
IDVHPGGDNI IVGTYDKRLL WHDLDLSNKP YKTLRFHKEA IRAVKFHQGG LPLFADASDD
GSLQIFHGKV VDDLMENATI VPLKVLRGHK VKSRLGVMDL DWHPREPWCV SAGADGTLRL
WN
