AGP41_ARATH
ID AGP41_ARATH Reviewed; 63 AA.
AC Q8L9T8;
DT 28-MAR-2018, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Arabinogalactan protein 41 {ECO:0000303|PubMed:15322080};
DE Short=AtAGP41 {ECO:0000303|PubMed:15322080};
DE AltName: Full=Arabinogalactan peptide 41 {ECO:0000303|PubMed:15322080};
DE Short=AG-peptide 41 {ECO:0000303|PubMed:15322080};
DE Flags: Precursor;
GN Name=AGP41 {ECO:0000303|PubMed:15322080};
GN OrderedLocusNames=At5g24105 {ECO:0000312|Araport:AT5G24105};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT features of the regions of 1,381,565 bp covered by twenty one physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:131-145(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP PROTEIN SEQUENCE OF 28-38, HYDROXYLATION AT PRO-32; PRO-34 AND PRO-36,
RP PYROGLUTAMATE FORMATION AT GLN-28, GLYCOSYLATION AT PRO-32; PRO-34 AND
RP PRO-36, AND GPI-ANCHOR AT SER-38.
RX PubMed=15322080; DOI=10.1074/jbc.m407594200;
RA Schultz C.J., Ferguson K.L., Lahnstein J., Bacic A.;
RT "Post-translational modifications of arabinogalactan-peptides of
RT Arabidopsis thaliana. Endoplasmic reticulum and
RT glycosylphosphatidylinositol-anchor signal cleavage sites and hydroxylation
RT of proline.";
RL J. Biol. Chem. 279:45503-45511(2004).
CC -!- FUNCTION: Proteoglycan that seems to be implicated in diverse
CC developmental roles such as differentiation, cell-cell recognition,
CC embryogenesis and programmed cell death. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC anchor {ECO:0000269|PubMed:15322080}.
CC -!- PTM: Contains 4-hydroxyproline; hydroxylated on Pro-32, Pro-34 and Pro-
CC 36. {ECO:0000269|PubMed:15322080}.
CC -!- PTM: O-glycosylated on hydroxyprolines; noncontiguous hydroxylproline
CC residues are glycosylated with arabinogalactan.
CC {ECO:0000305|PubMed:15322080}.
CC -!- SIMILARITY: Belongs to the AG-peptide AGP family. {ECO:0000305}.
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DR EMBL; AB010696; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED93257.1; -; Genomic_DNA.
DR EMBL; AK221000; BAD94646.1; -; mRNA.
DR EMBL; AK220598; BAD94927.1; -; mRNA.
DR EMBL; BT025631; ABF74692.1; -; mRNA.
DR EMBL; AY088224; AAM65765.1; -; mRNA.
DR RefSeq; NP_974828.1; NM_203099.2.
DR AlphaFoldDB; Q8L9T8; -.
DR STRING; 3702.AT5G24105.1; -.
DR PaxDb; Q8L9T8; -.
DR EnsemblPlants; AT5G24105.1; AT5G24105.1; AT5G24105.
DR GeneID; 2745995; -.
DR Gramene; AT5G24105.1; AT5G24105.1; AT5G24105.
DR KEGG; ath:AT5G24105; -.
DR Araport; AT5G24105; -.
DR TAIR; locus:1006230578; AT5G24105.
DR eggNOG; ENOG502S708; Eukaryota.
DR HOGENOM; CLU_187330_1_1_1; -.
DR InParanoid; Q8L9T8; -.
DR OMA; CTIISPV; -.
DR PhylomeDB; Q8L9T8; -.
DR PRO; PR:Q8L9T8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q8L9T8; baseline and differential.
DR GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR009424; AGP16/20/22/41.
DR PANTHER; PTHR33374; PTHR33374; 1.
DR Pfam; PF06376; AGP; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Direct protein sequencing; Glycoprotein; GPI-anchor;
KW Hydroxylation; Lipoprotein; Membrane; Proteoglycan;
KW Pyrrolidone carboxylic acid; Reference proteome; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000269|PubMed:15322080"
FT PEPTIDE 28..38
FT /note="Arabinogalactan protein 41"
FT /evidence="ECO:0000269|PubMed:15322080"
FT /id="PRO_0000443531"
FT PROPEP 39..63
FT /note="Removed in mature form"
FT /evidence="ECO:0000305|PubMed:15322080"
FT /id="PRO_0000443532"
FT MOD_RES 28
FT /note="Pyrrolidone carboxylic acid"
FT /evidence="ECO:0000269|PubMed:15322080"
FT MOD_RES 32
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000269|PubMed:15322080"
FT MOD_RES 34
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000269|PubMed:15322080"
FT MOD_RES 36
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000269|PubMed:15322080"
FT LIPID 38
FT /note="GPI-anchor amidated serine"
FT /evidence="ECO:0000269|PubMed:15322080"
FT CARBOHYD 32
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000305|PubMed:15322080"
FT CARBOHYD 34
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000305|PubMed:15322080"
FT CARBOHYD 36
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000305|PubMed:15322080"
SQ SEQUENCE 63 AA; 6574 MW; 9042F95BB7382202 CRC64;
MSGSRLFFGV STIVSIIFAI LLPMAHAQSA APAPAPTSDG TTIDQGIAYV LMLVALVLTY
LIH
