ERDL1_ARATH
ID ERDL1_ARATH Reviewed; 464 AA.
AC Q9SCW7; O04041;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 28-NOV-2006, sequence version 2.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Sugar transporter ERD6-like 1;
DE AltName: Full=Sugar transporter-like protein 4;
GN Name=SUGTL4; OrderedLocusNames=At1g08890; ORFNames=F7G19.23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 64-307.
RA Gy I., Kreis M., Lecharny A.;
RT "A novel multigene family in Arabidopsis thaliana coding for putative sugar
RT transporters.";
RL Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY.
RX PubMed=16923188; DOI=10.1186/1471-2148-6-64;
RA Johnson D.A., Hill J.P., Thomas M.A.;
RT "The monosaccharide transporter gene family in land plants is ancient and
RT shows differential subfamily expression and expansion across lineages.";
RL BMC Evol. Biol. 6:64-64(2006).
CC -!- FUNCTION: Sugar transporter. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB70415.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC000106; AAB70415.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE28362.1; -; Genomic_DNA.
DR EMBL; AJ249970; CAB64735.1; -; mRNA.
DR PIR; F86220; F86220.
DR RefSeq; NP_172364.3; NM_100761.4.
DR AlphaFoldDB; Q9SCW7; -.
DR SMR; Q9SCW7; -.
DR BioGRID; 22651; 23.
DR IntAct; Q9SCW7; 23.
DR STRING; 3702.AT1G08890.1; -.
DR PaxDb; Q9SCW7; -.
DR PRIDE; Q9SCW7; -.
DR ProteomicsDB; 220779; -.
DR EnsemblPlants; AT1G08890.1; AT1G08890.1; AT1G08890.
DR GeneID; 837410; -.
DR Gramene; AT1G08890.1; AT1G08890.1; AT1G08890.
DR KEGG; ath:AT1G08890; -.
DR Araport; AT1G08890; -.
DR TAIR; locus:2036039; AT1G08890.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_001265_30_5_1; -.
DR InParanoid; Q9SCW7; -.
DR OMA; AMYGRER; -.
DR OrthoDB; 430696at2759; -.
DR PhylomeDB; Q9SCW7; -.
DR PRO; PR:Q9SCW7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SCW7; baseline and differential.
DR Genevisible; Q9SCW7; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR CDD; cd17358; MFS_GLUT6_8_Class3_like; 1.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR044775; MFS_ERD6/Tret1-like.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Sugar transport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..464
FT /note="Sugar transporter ERD6-like 1"
FT /id="PRO_0000259850"
FT TRANSMEM 23..43
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 72..92
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 95..115
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 125..145
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 156..176
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 180..200
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 263..283
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 298..318
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 326..346
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 359..379
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 399..419
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TRANSMEM 424..444
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT CONFLICT 74..76
FT /note="TLG -> PLE (in Ref. 3; CAB64735)"
FT /evidence="ECO:0000305"
FT CONFLICT 101
FT /note="D -> N (in Ref. 3; CAB64735)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 464 AA; 50966 MW; BC57CEAE39B41849 CRC64;
MESGSMKTPL VNNQEEARSS SSITCGLLLS TSVAVTGSFV YGCAMSYSSP AQSKIMEELG
LSVADYSFFT SVMTLGGMIT AAFSGKIAAV IGRRQTMWIA DVFCIFGWLA VAFAHDKMLL
NIGRGFLGFG VGLISYVVPV YIAEITPKAF RGGFSFSNQL LQSFGISLMF FTGNFFHWRT
LALLSAIPCG IQMICLFFIP ESPRWLAMYG RERELEVTLK RLRGENGDIL EEAAEIRETV
ETSRRESRSG LKDLFNMKNA HPLIIGLGLM LLQQFCGSSA ISAYAARIFD TAGFPSDIGT
SILAVILVPQ SIIVMFAVDR CGRRPLLMSS SIGLCICSFL IGLSYYLQNH GDFQEFCSPI
LIVGLVGYVL SFGIGLGGLP WVIMSEVFPV NVKITAGSLV TVSNWFFSWI IIFSFNFMMQ
WSAFGTYFIF AGVSLMSFVF VWTLVPETKG RTLEDIQQSL GQLS
