ERDL7_ARATH
ID ERDL7_ARATH Reviewed; 463 AA.
AC P93051; Q8LFR8; Q9ZU87;
DT 14-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 14-NOV-2006, sequence version 2.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Sugar transporter ERD6-like 7;
GN OrderedLocusNames=At2g48020; ORFNames=T9J23.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-121.
RC STRAIN=cv. C24;
RX PubMed=9484433; DOI=10.1023/a:1005902730810;
RA Kertbundit S., Linacero R., Rouze P., Galis I., Macas J., Deboeck F.,
RA Renckens S., Hernalsteens J.-P., de Greve H.;
RT "Analysis of T-DNA-mediated translational beta-glucuronidase gene
RT fusions.";
RL Plant Mol. Biol. 36:205-217(1998).
RN [6]
RP GENE FAMILY.
RX PubMed=16923188; DOI=10.1186/1471-2148-6-64;
RA Johnson D.A., Hill J.P., Thomas M.A.;
RT "The monosaccharide transporter gene family in land plants is ancient and
RT shows differential subfamily expression and expansion across lineages.";
RL BMC Evol. Biol. 6:64-64(2006).
CC -!- FUNCTION: Sugar transporter. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
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DR EMBL; AC006072; AAD13706.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC10924.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10925.1; -; Genomic_DNA.
DR EMBL; AY120715; AAM53273.1; -; mRNA.
DR EMBL; BT000053; AAN15372.1; -; mRNA.
DR EMBL; AY084684; AAM61246.1; -; mRNA.
DR EMBL; Z84202; CAB06336.1; -; Genomic_DNA.
DR PIR; D84922; D84922.
DR RefSeq; NP_566120.1; NM_130369.4.
DR RefSeq; NP_850483.1; NM_180152.3.
DR AlphaFoldDB; P93051; -.
DR SMR; P93051; -.
DR BioGRID; 4749; 1.
DR STRING; 3702.AT2G48020.1; -.
DR PaxDb; P93051; -.
DR PRIDE; P93051; -.
DR ProteomicsDB; 221852; -.
DR EnsemblPlants; AT2G48020.1; AT2G48020.1; AT2G48020.
DR EnsemblPlants; AT2G48020.2; AT2G48020.2; AT2G48020.
DR GeneID; 819414; -.
DR Gramene; AT2G48020.1; AT2G48020.1; AT2G48020.
DR Gramene; AT2G48020.2; AT2G48020.2; AT2G48020.
DR KEGG; ath:AT2G48020; -.
DR Araport; AT2G48020; -.
DR TAIR; locus:2066400; AT2G48020.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_001265_30_5_1; -.
DR InParanoid; P93051; -.
DR OMA; TCPMGYI; -.
DR OrthoDB; 430696at2759; -.
DR PhylomeDB; P93051; -.
DR PRO; PR:P93051; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; P93051; baseline and differential.
DR Genevisible; P93051; AT.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR GO; GO:0006829; P:zinc ion transport; IMP:TAIR.
DR CDD; cd17358; MFS_GLUT6_8_Class3_like; 1.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR044775; MFS_ERD6/Tret1-like.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Sugar transport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..463
FT /note="Sugar transporter ERD6-like 7"
FT /id="PRO_0000259857"
FT TRANSMEM 26..46
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 103..123
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 126..146
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 157..177
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 181..201
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 264..284
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 299..319
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 327..347
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 357..377
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 396..416
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TRANSMEM 426..446
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT CONFLICT 39
FT /note="S -> P (in Ref. 4; AAM61246)"
FT /evidence="ECO:0000305"
FT CONFLICT 117..121
FT /note="GVVAL -> VLLRI (in Ref. 5; CAB06336)"
FT /evidence="ECO:0000305"
FT CONFLICT 460
FT /note="I -> V (in Ref. 4; AAM61246)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 463 AA; 49700 MW; 7C6B761D77A59CD3 CRC64;
MSKASDAVRE PLVDKNMAGS KPDQPWMVYL STFVAVCGSF AFGSCAGYSS PAQAAIRNDL
SLTIAEFSLF GSLLTFGAMI GAITSGPIAD LVGRKGAMRV SSAFCVVGWL AIIFAKGVVA
LDLGRLATGY GMGAFSYVVP IFIAEIAPKT FRGALTTLNQ ILICTGVSVS FIIGTLVTWR
VLALIGIIPC AASFLGLFFI PESPRWLAKV GRDTEFEAAL RKLRGKKADI SEEAAEIQDY
IETLERLPKA KMLDLFQRRY IRSVLIAFGL MVFQQFGGIN GICFYTSSIF EQAGFPTRLG
MIIYAVLQVV ITALNAPIVD RAGRKPLLLV SATGLVIGCL IAAVSFYLKV HDMAHEAVPV
LAVVGIMVYI GSFSAGMGAM PWVVMSEIFP INIKGVAGGM ATLVNWFGAW AVSYTFNFLM
SWSSYGTFLI YAAINALAIV FVIAIVPETK GKTLEQIQAI VNP
