ID   ERF18_ARATH             Reviewed;         195 AA.
AC   Q9S7L5;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=Ethylene-responsive transcription factor ERF018;
GN   Name=ERF018; OrderedLocusNames=At1g74930; ORFNames=F25A4.10, F9E10.22;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16407444; DOI=10.1104/pp.105.073783;
RA   Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT   "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL   Plant Physiol. 140:411-432(2006).
CC   -!- FUNCTION: Probably acts as a transcriptional activator. Binds to the
CC       GCC-box pathogenesis-related promoter element. May be involved in the
CC       regulation of gene expression by stress factors and by components of
CC       stress signal transduction pathways (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC       subfamily. {ECO:0000305}.
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DR   EMBL; AC008263; AAD55283.1; -; Genomic_DNA.
DR   EMBL; AC013258; AAG51936.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE35652.1; -; Genomic_DNA.
DR   EMBL; AY128309; AAM91512.1; -; mRNA.
DR   EMBL; BT003348; AAO29966.1; -; mRNA.
DR   PIR; A96779; A96779.
DR   RefSeq; NP_177631.1; NM_106151.3.
DR   AlphaFoldDB; Q9S7L5; -.
DR   SMR; Q9S7L5; -.
DR   BioGRID; 29051; 14.
DR   IntAct; Q9S7L5; 3.
DR   STRING; 3702.AT1G74930.1; -.
DR   PaxDb; Q9S7L5; -.
DR   PRIDE; Q9S7L5; -.
DR   EnsemblPlants; AT1G74930.1; AT1G74930.1; AT1G74930.
DR   GeneID; 843832; -.
DR   Gramene; AT1G74930.1; AT1G74930.1; AT1G74930.
DR   KEGG; ath:AT1G74930; -.
DR   Araport; AT1G74930; -.
DR   TAIR; locus:2027171; AT1G74930.
DR   eggNOG; ENOG502RZQP; Eukaryota.
DR   HOGENOM; CLU_063331_2_1_1; -.
DR   InParanoid; Q9S7L5; -.
DR   OMA; FTHAEIQ; -.
DR   OrthoDB; 1385789at2759; -.
DR   PhylomeDB; Q9S7L5; -.
DR   PRO; PR:Q9S7L5; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9S7L5; baseline and differential.
DR   Genevisible; Q9S7L5; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR   GO; GO:0051301; P:cell division; IEP:TAIR.
DR   GO; GO:0002213; P:defense response to insect; IEP:TAIR.
DR   GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0010087; P:phloem or xylem histogenesis; IEP:TAIR.
DR   GO; GO:0009611; P:response to wounding; IEP:TAIR.
DR   CDD; cd00018; AP2; 1.
DR   Gene3D; 3.30.730.10; -; 1.
DR   InterPro; IPR001471; AP2/ERF_dom.
DR   InterPro; IPR036955; AP2/ERF_dom_sf.
DR   InterPro; IPR016177; DNA-bd_dom_sf.
DR   Pfam; PF00847; AP2; 1.
DR   PRINTS; PR00367; ETHRSPELEMNT.
DR   SMART; SM00380; AP2; 1.
DR   SUPFAM; SSF54171; SSF54171; 1.
DR   PROSITE; PS51032; AP2_ERF; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Ethylene signaling pathway; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..195
FT                   /note="Ethylene-responsive transcription factor ERF018"
FT                   /id="PRO_0000290378"
FT   DNA_BIND        20..77
FT                   /note="AP2/ERF"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   195 AA;  21898 MW;  76C50CB8012074EF CRC64;
     MVKQAMKEEE KKRNTAMQSK YKGVRKRKWG KWVSEIRLPH SRERIWLGSY DTPEKAARAF
     DAAQFCLRGG DANFNFPNNP PSISVEKSLT PPEIQEAAAR FANTFQDIVK GEEESGLVPG
     SEIRPESPST SASVATSTVD YDFSFLDLLP MNFGFDSFSD DFSGFSGGDR FTEILPIEDY
     GGESLLDESL ILWDF