ERF1_ORYSJ
ID ERF1_ORYSJ Reviewed; 365 AA.
AC Q6K7E6; Q9SE28;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Ethylene-responsive transcription factor 1;
DE AltName: Full=Ethylene-responsive element-binding factor 1;
DE Short=EREBP-1;
DE Short=OsEREBP1;
GN Name=EREBP1; OrderedLocusNames=Os02g0782700, LOC_Os02g54160;
GN ORFNames=OJ1311_D08.9;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INTERACTION WITH MPK12/BWMK1,
RP PHOSPHORYLATION, AND FUNCTION AS A TRANSCRIPTIONAL ACTIVATOR.
RX PubMed=12913152; DOI=10.1104/pp.103.023176;
RA Cheong Y.H., Moon B.C., Kim J.K., Kim C.Y., Kim M.C., Kim I.H., Park C.Y.,
RA Kim J.C., Park B.O., Koo S.C., Yoon H.W., Chung W.S., Lim C.O., Lee S.Y.,
RA Cho M.J.;
RT "BWMK1, a rice mitogen-activated protein kinase, locates in the nucleus and
RT mediates pathogenesis-related gene expression by activation of a
RT transcription factor.";
RL Plant Physiol. 132:1961-1972(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
CC -!- FUNCTION: Probable transcriptional activator that may be involved in
CC defense signaling pathway. Binds in vitro to the DNA sequence 5'-
CC AGCCGCC-3' of the GCC-box element found in pathogenesis-related (PR)
CC gene promoters. The transcriptional activation is enhanced in vitro by
CC the presence of MPK12/BWMK1. {ECO:0000269|PubMed:12913152}.
CC -!- SUBUNIT: Interacts with MPK12/BWMK1. {ECO:0000269|PubMed:12913152}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- DOMAIN: The AP2/ERF domain binds specifically to the 5'-GCCGCC-3'
CC motif. The affinity of this binding is higher if the seventh amino-acid
CC of this domain is basic (By similarity). {ECO:0000250}.
CC -!- PTM: Phosphorylated in vitro by MPK12/BWMK1.
CC {ECO:0000269|PubMed:12913152}.
CC -!- SIMILARITY: Belongs to the ethylene-response factor family. Class 1
CC subfamily. {ECO:0000305}.
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DR EMBL; AF193803; AAF23899.1; -; mRNA.
DR EMBL; AP004849; BAD19536.1; -; Genomic_DNA.
DR EMBL; AP014958; BAS81245.1; -; Genomic_DNA.
DR AlphaFoldDB; Q6K7E6; -.
DR SMR; Q6K7E6; -.
DR BioGRID; 799972; 1.
DR STRING; 4530.OS02T0782700-01; -.
DR PaxDb; Q6K7E6; -.
DR PRIDE; Q6K7E6; -.
DR EnsemblPlants; Os02t0782700-01; Os02t0782700-01; Os02g0782700.
DR EnsemblPlants; Os02t0782700-02; Os02t0782700-02; Os02g0782700.
DR Gramene; Os02t0782700-01; Os02t0782700-01; Os02g0782700.
DR Gramene; Os02t0782700-02; Os02t0782700-02; Os02g0782700.
DR eggNOG; ENOG502QV26; Eukaryota.
DR HOGENOM; CLU_054468_0_0_1; -.
DR InParanoid; Q6K7E6; -.
DR OMA; DDMPIAG; -.
DR PRO; PR:Q6K7E6; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR ExpressionAtlas; Q6K7E6; baseline and differential.
DR Genevisible; Q6K7E6; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:InterPro.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR044808; ERF_plant.
DR PANTHER; PTHR31190; PTHR31190; 1.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Nucleus; Phosphoprotein; Plant defense;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..365
FT /note="Ethylene-responsive transcription factor 1"
FT /id="PRO_0000239762"
FT DNA_BIND 119..176
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 176..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 113
FT /note="K -> Q (in Ref. 1; AAF23899)"
FT /evidence="ECO:0000305"
FT CONFLICT 125
FT /note="Q -> H (in Ref. 1; AAF23899)"
FT /evidence="ECO:0000305"
FT CONFLICT 165
FT /note="R -> T (in Ref. 1; AAF23899)"
FT /evidence="ECO:0000305"
FT CONFLICT 171
FT /note="A -> P (in Ref. 1; AAF23899)"
FT /evidence="ECO:0000305"
FT CONFLICT 212
FT /note="L -> C (in Ref. 1; AAF23899)"
FT /evidence="ECO:0000305"
FT CONFLICT 216
FT /note="N -> M (in Ref. 1; AAF23899)"
FT /evidence="ECO:0000305"
FT CONFLICT 257
FT /note="D -> E (in Ref. 1; AAF23899)"
FT /evidence="ECO:0000305"
FT CONFLICT 313
FT /note="A -> G (in Ref. 1; AAF23899)"
FT /evidence="ECO:0000305"
FT CONFLICT 322
FT /note="Y -> N (in Ref. 1; AAF23899)"
FT /evidence="ECO:0000305"
FT CONFLICT 331
FT /note="A -> G (in Ref. 1; AAF23899)"
FT /evidence="ECO:0000305"
FT CONFLICT 339
FT /note="L -> F (in Ref. 1; AAF23899)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 365 AA; 40142 MW; 2E380CBDDA5B9513 CRC64;
MCGGAIIHHL KGHPEGSRRA TEGLLWPEKK KPRWGGGGRR HFGGFVEEDD EDFEADFEEF
EVDSGDSDLE LGEEDDDDVV EIKPAAFKRA LSRDNLSTIT TAGFDGPAAK SAKRKRKNQF
RGIRQRPWGK WAAEIRDPRK GVRVWLGTFN SAEEAARAYD AEARRIRGKK AKVNFPEAPT
TAQKRRAGST TAKAPKSSVE QKPTVKPAFN NLANANAFVY PSANFTSNKP FVQPDNMPFV
PAMNSAAPIE DPIINSDQGS NSFGCSDFGW ENDTKTPDIT SIAPISTIAE VDESAFIKSS
TNPMVPPVME NSAVDLPDLE PYMRFLLDDG AGDSIDSLLN LDGSQDVVSN MDLWSFDDMP
VSDFY
