ID   ERF1_PODAS              Reviewed;         435 AA.
AC   O59948;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Eukaryotic peptide chain release factor subunit 1;
DE            Short=Eukaryotic release factor 1;
DE            Short=eRF1;
GN   Name=SU2;
OS   Podospora anserina (Pleurage anserina).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Podosporaceae; Podospora.
OX   NCBI_TaxID=2587412;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=s;
RX   PubMed=9691035; DOI=10.1093/genetics/149.4.1763;
RA   Gagny B., Silar P.;
RT   "Identification of the genes encoding the cytosolic translation release
RT   factors from Podospora anserina and analysis of their role during the life
RT   cycle.";
RL   Genetics 149:1763-1775(1998).
CC   -!- FUNCTION: Directs the termination of nascent peptide synthesis
CC       (translation) in response to the termination codons UAA, UAG and UGA.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of two subunits, one of which binds GTP.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eukaryotic release factor 1 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF053983; AAC08410.1; -; Genomic_DNA.
DR   AlphaFoldDB; O59948; -.
DR   SMR; O59948; -.
DR   VEuPathDB; FungiDB:PODANS_7_8260; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003747; F:translation release factor activity; IEA:InterPro.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   Gene3D; 3.30.420.60; -; 1.
DR   Gene3D; 3.30.960.10; -; 1.
DR   InterPro; IPR042226; eFR1_2_sf.
DR   InterPro; IPR005140; eRF1_1_Pelota.
DR   InterPro; IPR024049; eRF1_1_sf.
DR   InterPro; IPR005141; eRF1_2.
DR   InterPro; IPR005142; eRF1_3.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR004403; Peptide_chain-rel_eRF1/aRF1.
DR   PANTHER; PTHR10113; PTHR10113; 1.
DR   Pfam; PF03463; eRF1_1; 1.
DR   Pfam; PF03464; eRF1_2; 1.
DR   Pfam; PF03465; eRF1_3; 1.
DR   SMART; SM01194; eRF1_1; 1.
DR   SUPFAM; SSF55315; SSF55315; 1.
DR   SUPFAM; SSF55481; SSF55481; 1.
DR   TIGRFAMs; TIGR03676; aRF1/eRF1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Protein biosynthesis.
FT   CHAIN           1..435
FT                   /note="Eukaryotic peptide chain release factor subunit 1"
FT                   /id="PRO_0000143165"
SQ   SEQUENCE   435 AA;  48916 MW;  A2DD5AB6940E33F9 CRC64;
     MSDPNANEAE KNIEIWKVKK LIKRLEAARG NGTSMISLII PPKDQISRAA KMLAEEYGTA
     SNIKSRVNRQ SVLSAITSTQ QRLKLYNKVP PNGLVVYCGE ILTSEGKERK VNIDFEPFKP
     INTSLYLCDN KFHTEALAEL LESDQKFGFI VMDGNGALFG TLSGNTRDIV HKFSVDLPKK
     HGRGGQSALR FARLREEKRH NYVRKVAELA VQNFITNDKV NVMGIVLAGS ADFKNDLNAS
     DMFDQRLATK VIKVVDVSYG GENGFNQAIE LASETLGNVK FIQEKKLIGK YFEEISQDTG
     RICYGVEDTL KALELGAVET LIVFENLEVT RWVLKDSNGA EIIIHSTKQQ DAANRDRFMD
     KETGQEMEVV SQESFLEWIA EHYKDFGTTL EFVSDRSTEG NQFVKGFGGI GGILRYKVNF
     EQLNEVDDDD EYYDD