ID   ERF1_POLMI              Reviewed;         435 AA.
AC   Q9GR88;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Eukaryotic peptide chain release factor subunit 1;
DE            Short=Eukaryotic release factor 1;
DE            Short=eRF1;
GN   Name=ERF1;
OS   Polyandrocarpa misakiensis (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Stolidobranchia;
OC   Styelidae; Polyandrocarpa.
OX   NCBI_TaxID=7723;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Sagara Y., Fujiwara S., Yubisui T.;
RT   "cDNA clonings from Polyandrocarpa misakiensis.";
RL   Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Directs the termination of nascent peptide synthesis
CC       (translation) in response to the termination codons UAA, UAG and UGA.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of two subunits, one of which binds GTP.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eukaryotic release factor 1 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB053116; BAB20047.1; -; mRNA.
DR   AlphaFoldDB; Q9GR88; -.
DR   SMR; Q9GR88; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003747; F:translation release factor activity; IEA:InterPro.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   Gene3D; 3.30.420.60; -; 1.
DR   Gene3D; 3.30.960.10; -; 1.
DR   InterPro; IPR042226; eFR1_2_sf.
DR   InterPro; IPR005140; eRF1_1_Pelota.
DR   InterPro; IPR024049; eRF1_1_sf.
DR   InterPro; IPR005141; eRF1_2.
DR   InterPro; IPR005142; eRF1_3.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR004403; Peptide_chain-rel_eRF1/aRF1.
DR   PANTHER; PTHR10113; PTHR10113; 1.
DR   Pfam; PF03463; eRF1_1; 1.
DR   Pfam; PF03464; eRF1_2; 1.
DR   Pfam; PF03465; eRF1_3; 1.
DR   SMART; SM01194; eRF1_1; 1.
DR   SUPFAM; SSF55315; SSF55315; 1.
DR   SUPFAM; SSF55481; SSF55481; 1.
DR   TIGRFAMs; TIGR03676; aRF1/eRF1; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Protein biosynthesis.
FT   CHAIN           1..435
FT                   /note="Eukaryotic peptide chain release factor subunit 1"
FT                   /id="PRO_0000143157"
SQ   SEQUENCE   435 AA;  49110 MW;  6E0FC47D6B9A7BD0 CRC64;
     MAETETTADR NVEIWKIKKL IKSLEAARGN GTSMISLIIP PKDQVSRVAK MLADEFGTAS
     NIKSRVNRLS VLGAITSVQQ RLKLYNKVPP NGLVVYCGTI VTDEGKEKKV NIDFEPFKPI
     NTSLYLCDNK FHTEALTALL SDDNKFGFIV MDGNGALFGT LQGNTREVLH KFTVDLPKKH
     GRGGQSALRF ARLRMEKRHN YVRKVAETAV QLFITNDRPN VTGLVLAGSA DFKTELSQSD
     MFDQRLQVKI LKLVDVSYGG ENGFNQAIEL SAEVLSNVKF IQEKKLIGRY FDEISQDTGK
     YCFGVDDTLK ALEMGAVEIL IVWENLDTMR YVLKNHTTDE EKILFLKPDQ EKDKTHFTDK
     DTGVEMEMVE SCSLLEWFAN NYKKFGSTLE IVTDRSQEGS QFVKGFGGIG GMLRYRIDFQ
     GMEFNDDDPD LYDDY