ERF69_ARATH
ID ERF69_ARATH Reviewed; 159 AA.
AC Q8W4I5;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Ethylene-responsive transcription factor ERF069;
GN Name=ERF069; OrderedLocusNames=At1g22985; ORFNames=F19G10.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Probably acts as a transcriptional activator. Binds to the
CC GCC-box pathogenesis-related promoter element. May be involved in the
CC regulation of gene expression by stress factors and by components of
CC stress signal transduction pathways (By similarity). {ECO:0000250}.
CC -!- INTERACTION:
CC Q8W4I5; Q9SUQ2: CRF2; NbExp=3; IntAct=EBI-5568301, EBI-5567273;
CC Q8W4I5; Q9FK12: CRF3; NbExp=3; IntAct=EBI-5568301, EBI-5567993;
CC Q8W4I5; Q9SUE3: CRF4; NbExp=3; IntAct=EBI-5568301, EBI-5567027;
CC Q8W4I5; O82339: CRF5; NbExp=3; IntAct=EBI-5568301, EBI-5567180;
CC Q8W4I5; Q9M374: CRF6; NbExp=3; IntAct=EBI-5568301, EBI-5568101;
CC Q8W4I5; Q9C995: ERF070; NbExp=3; IntAct=EBI-5568301, EBI-5568333;
CC Q8W4I5; Q9M2V2: T12E18_40; NbExp=6; IntAct=EBI-5568301, EBI-15192147;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
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DR EMBL; AF000657; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE30318.1; -; Genomic_DNA.
DR EMBL; AY062541; AAL32619.1; -; mRNA.
DR EMBL; AY093336; AAM13335.1; -; mRNA.
DR EMBL; AY087064; AAM64625.1; -; mRNA.
DR RefSeq; NP_564186.1; NM_102146.3.
DR AlphaFoldDB; Q8W4I5; -.
DR SMR; Q8W4I5; -.
DR BioGRID; 24145; 17.
DR IntAct; Q8W4I5; 16.
DR STRING; 3702.AT1G22985.1; -.
DR PaxDb; Q8W4I5; -.
DR PRIDE; Q8W4I5; -.
DR ProteomicsDB; 220626; -.
DR EnsemblPlants; AT1G22985.1; AT1G22985.1; AT1G22985.
DR GeneID; 838906; -.
DR Gramene; AT1G22985.1; AT1G22985.1; AT1G22985.
DR KEGG; ath:AT1G22985; -.
DR Araport; AT1G22985; -.
DR TAIR; locus:505006142; AT1G22985.
DR eggNOG; ENOG502R7AV; Eukaryota.
DR HOGENOM; CLU_062946_3_0_1; -.
DR InParanoid; Q8W4I5; -.
DR OMA; YIMDNDA; -.
DR OrthoDB; 1450756at2759; -.
DR PhylomeDB; Q8W4I5; -.
DR PRO; PR:Q8W4I5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8W4I5; baseline and differential.
DR Genevisible; Q8W4I5; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR017392; AP2/ERF-transcript_factor.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 1.
DR PIRSF; PIRSF038123; PTI6; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Ethylene signaling pathway; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..159
FT /note="Ethylene-responsive transcription factor ERF069"
FT /id="PRO_0000290404"
FT DNA_BIND 74..134
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 159 AA; 17536 MW; 7F509CE718A24497 CRC64;
MKRIVRISFT DMEATDSSSS EDESPPSSRR RGKKLVKEIV IDHSDPPEVG KTRFKIRIPA
SLLAARNTTA NKKKFRGVRQ RPWGKWAAEI RCGRVKGRPE RIWLGTFETA EEAALAYDNA
AIQLIGPDAP TNFGRPDVDS AVVKKQDSDA SGGASEEVV
