ID   AGR11_AGRAE             Reviewed;         355 AA.
AC   A0A5Q0QRK8;
DT   07-OCT-2020, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2020, sequence version 1.
DT   03-AUG-2022, entry version 7.
DE   RecName: Full=Sesquiterpene synthase-like protein Agr11 {ECO:0000303|PubMed:32233445};
GN   Name=Agr11 {ECO:0000303|PubMed:32233445};
OS   Agrocybe aegerita (Black poplar mushroom) (Agaricus aegerita).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Bolbitiaceae; Cyclocybe.
OX   NCBI_TaxID=1973307;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND IDENTIFICATION.
RC   STRAIN=AAE3_05024;
RX   PubMed=32233445; DOI=10.1021/acschembio.0c00155;
RA   Zhang C., Chen X., Orban A., Shukal S., Birk F., Too H.P., Ruehl M.;
RT   "Agrocybe aegerita serves as a gateway for identifying sesquiterpene
RT   biosynthetic enzymes in higher fungi.";
RL   ACS Chem. Biol. 15:1268-1277(2020).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AAE3_05024;
RX   PubMed=29334897; DOI=10.1186/s12864-017-4430-y;
RA   Gupta D.K., Ruehl M., Mishra B., Kleofas V., Hofrichter M., Herzog R.,
RA   Pecyna M.J., Sharma R., Kellner H., Hennicke F., Thines M.;
RT   "The genome sequence of the commercially cultivated mushroom Agrocybe
RT   aegerita reveals a conserved repertoire of fruiting-related genes and a
RT   versatile suite of biopolymer-degrading enzymes.";
RL   BMC Genomics 19:48-48(2018).
CC   -!- SIMILARITY: Belongs to the terpene synthase family. {ECO:0000305}.
CC   -!- CAUTION: Does not functions as a sesquiterpene synthase since it does
CC       not contain a functional DDXXD metal-binding motif.
CC       {ECO:0000269|PubMed:32233445}.
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DR   EMBL; MN146034; QGA30887.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A5Q0QRK8; -.
DR   SMR; A0A5Q0QRK8; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.600.10; -; 1.
DR   InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR   SUPFAM; SSF48576; SSF48576; 1.
PE   3: Inferred from homology;
KW   Magnesium; Metal-binding.
FT   CHAIN           1..355
FT                   /note="Sesquiterpene synthase-like protein Agr11"
FT                   /id="PRO_0000451265"
SQ   SEQUENCE   355 AA;  40172 MW;  44B8CBC69A5871DF CRC64;
     MQIILPDILQ TWAYARLLNP HYDGAKLESS LWIHPLVAKL FDQKGQKAFQ NDYTSLLASL
     MYSHQGKVPS RRCDMMNLFF VYDEYTDVVS PEIAHRLSKI VVDAMKNSDE MSPCGEHPIG
     DKAKEFWRLA TTLLPATGSN SDVCKSRFIN LTEEYLNAVT VEARDRNEGT IHSVKEYLTM
     RRATSGAGLM LALIEFELDL PKAVLEHKFV QALEEIYTRT RVSSGQANHN LITVVMHENP
     GLSLQGAFDW LGSYAAGVVE CFQTNVRNLP SFCDVEGPAC ESVDGTLQER VDKYISGLGQ
     AVRAEDDWAF ETTRYYGEDG PKVRETRVLV IRPVKRITRR HLLQSLEIKY SMVRG