ERF79_ARATH
ID ERF79_ARATH Reviewed; 185 AA.
AC Q9MAI5;
DT 04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Ethylene-responsive transcription factor 8;
DE Short=AtERF8;
DE AltName: Full=Ethylene-responsive element-binding factor 8;
DE Short=EREBP-8;
GN Name=ERF8; Synonyms=ERF-8, ERF079; OrderedLocusNames=At1g53170;
GN ORFNames=F12M16.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND DOMAIN.
RX PubMed=11487705; DOI=10.2307/3871331;
RA Ohta M., Matsui K., Hiratsu K., Shinshi H., Ohme-Takagi M.;
RT "Repression domains of class II ERF transcriptional repressors share an
RT essential motif for active repression.";
RL Plant Cell 13:1959-1968(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Involved in the regulation of gene expression by stress
CC factors and by components of stress signal transduction pathways.
CC Transcription factor that binds to the GCC-box pathogenesis-related
CC promoter element. Acts as a transcriptional inhibitor and may regulate
CC other AtERFs (By similarity). {ECO:0000250,
CC ECO:0000269|PubMed:11487705}.
CC -!- INTERACTION:
CC Q9MAI5; Q9FIW5: ANAC094; NbExp=3; IntAct=EBI-2000137, EBI-25522986;
CC Q9MAI5; Q93YR9: ARF16; NbExp=3; IntAct=EBI-2000137, EBI-3947588;
CC Q9MAI5; Q94C33: At3g51180; NbExp=3; IntAct=EBI-2000137, EBI-4438678;
CC Q9MAI5; O80748: B-box domain protein 26; NbExp=3; IntAct=EBI-2000137, EBI-15191535;
CC Q9MAI5; Q38897: BEL1; NbExp=3; IntAct=EBI-2000137, EBI-1153783;
CC Q9MAI5; Q9C7T4: BHLH96; NbExp=3; IntAct=EBI-2000137, EBI-15192637;
CC Q9MAI5; Q8L765: BPM1; NbExp=3; IntAct=EBI-2000137, EBI-540891;
CC Q9MAI5; O22286: BPM3; NbExp=3; IntAct=EBI-2000137, EBI-540923;
CC Q9MAI5; Q17TI5: BRX; NbExp=3; IntAct=EBI-2000137, EBI-4426649;
CC Q9MAI5; Q9SVX5: DREB2F; NbExp=3; IntAct=EBI-2000137, EBI-15195807;
CC Q9MAI5; Q9SKT1: ERF053; NbExp=3; IntAct=EBI-2000137, EBI-25511859;
CC Q9MAI5; Q6J9Q2: ERF086; NbExp=3; IntAct=EBI-2000137, EBI-15202888;
CC Q9MAI5; Q9FYK5: ESR2; NbExp=3; IntAct=EBI-2000137, EBI-1536925;
CC Q9MAI5; Q9LQT8: GAI; NbExp=3; IntAct=EBI-2000137, EBI-963606;
CC Q9MAI5; Q9LS00: HHO1; NbExp=4; IntAct=EBI-2000137, EBI-15203988;
CC Q9MAI5; Q8VZS3: HHO2; NbExp=3; IntAct=EBI-2000137, EBI-4429217;
CC Q9MAI5; Q9CA30: LBD42; NbExp=3; IntAct=EBI-2000137, EBI-25523506;
CC Q9MAI5; Q9LSI4: MGH6.1; NbExp=3; IntAct=EBI-2000137, EBI-15198743;
CC Q9MAI5; Q9LK95: MYB21; NbExp=3; IntAct=EBI-2000137, EBI-15197631;
CC Q9MAI5; O22179: MYB70; NbExp=3; IntAct=EBI-2000137, EBI-1238013;
CC Q9MAI5; O23160: MYB73; NbExp=5; IntAct=EBI-2000137, EBI-25506855;
CC Q9MAI5; Q9FK47: MYR1; NbExp=3; IntAct=EBI-2000137, EBI-25523464;
CC Q9MAI5; Q9SFD8: NFYB9; NbExp=3; IntAct=EBI-2000137, EBI-2475789;
CC Q9MAI5; Q8LAJ7: PHL3; NbExp=3; IntAct=EBI-2000137, EBI-4443730;
CC Q9MAI5; Q38845: PP2AA1; NbExp=3; IntAct=EBI-2000137, EBI-1645478;
CC Q9MAI5; O82239: RFI2; NbExp=3; IntAct=EBI-2000137, EBI-4425094;
CC Q9MAI5; Q9S7W5: TCP13; NbExp=5; IntAct=EBI-2000137, EBI-4424877;
CC Q9MAI5; Q9C9L2: TCP15; NbExp=3; IntAct=EBI-2000137, EBI-4426144;
CC Q9MAI5; Q9M1U4: TCP16; NbExp=3; IntAct=EBI-2000137, EBI-15198627;
CC Q9MAI5; Q9FTA2: TCP21; NbExp=3; IntAct=EBI-2000137, EBI-4426168;
CC Q9MAI5; Q9LQF0: TCP23; NbExp=4; IntAct=EBI-2000137, EBI-15192297;
CC Q9MAI5; Q9MAH8: TCP3; NbExp=3; IntAct=EBI-2000137, EBI-25522447;
CC Q9MAI5; Q9LVG2: TOE2; NbExp=3; IntAct=EBI-2000137, EBI-4424568;
CC Q9MAI5; Q5CCK4: VAL2; NbExp=3; IntAct=EBI-2000137, EBI-15193683;
CC Q9MAI5; O22152: YAB1; NbExp=3; IntAct=EBI-2000137, EBI-1113627;
CC Q9MAI5; Q9LDT3: YAB4; NbExp=3; IntAct=EBI-2000137, EBI-1115523;
CC Q9MAI5; O64722: ZHD3; NbExp=3; IntAct=EBI-2000137, EBI-1806244;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- DOMAIN: Contains a slightly degenerated ERF-associated amphiphilic
CC repression (EAR) motif, which may be involved in the activity of
CC transcriptional repression. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB036884; BAB16084.1; -; mRNA.
DR EMBL; AC008007; AAF69554.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32902.1; -; Genomic_DNA.
DR EMBL; AK117541; BAC42202.1; -; mRNA.
DR EMBL; BT005401; AAO63821.1; -; mRNA.
DR PIR; D96572; D96572.
DR RefSeq; NP_175725.1; NM_104196.3.
DR AlphaFoldDB; Q9MAI5; -.
DR SMR; Q9MAI5; -.
DR BioGRID; 26976; 56.
DR IntAct; Q9MAI5; 45.
DR STRING; 3702.AT1G53170.1; -.
DR iPTMnet; Q9MAI5; -.
DR PaxDb; Q9MAI5; -.
DR PRIDE; Q9MAI5; -.
DR ProteomicsDB; 220627; -.
DR EnsemblPlants; AT1G53170.1; AT1G53170.1; AT1G53170.
DR GeneID; 841751; -.
DR Gramene; AT1G53170.1; AT1G53170.1; AT1G53170.
DR KEGG; ath:AT1G53170; -.
DR Araport; AT1G53170; -.
DR TAIR; locus:2009655; AT1G53170.
DR eggNOG; ENOG502RYHH; Eukaryota.
DR HOGENOM; CLU_042594_5_1_1; -.
DR InParanoid; Q9MAI5; -.
DR OMA; HESNAAK; -.
DR OrthoDB; 1613217at2759; -.
DR PhylomeDB; Q9MAI5; -.
DR PRO; PR:Q9MAI5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9MAI5; baseline and differential.
DR Genevisible; Q9MAI5; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; TAS:TAIR.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Ethylene signaling pathway; Nucleus; Reference proteome;
KW Repressor; Transcription; Transcription regulation.
FT CHAIN 1..185
FT /note="Ethylene-responsive transcription factor 8"
FT /id="PRO_0000112558"
FT DNA_BIND 30..87
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 176..182
FT /note="EAR-like (transcriptional repression)"
SQ SEQUENCE 185 AA; 20025 MW; 810F4C4EDEFF9DA5 CRC64;
MPNITMGLKP DPVAPTNPTH HESNAAKEIR YRGVRKRPWG RYAAEIRDPV KKTRVWLGTF
DTAQQAARAY DAAARDFRGV KAKTNFGVIV GSSPTQSSTV VDSPTAARFI TPPHLELSLG
GGGACRRKIP LVHPVYYYNM ATYPKMTTCG VQSESETSSV VDFEGGAGKI SPPLDLDLNL
APPAE
