ID   ERF93_ARATH             Reviewed;         243 AA.
AC   Q8VYM0; Q9SJX3;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Ethylene-responsive transcription factor 15;
DE            Short=AtERF15;
DE   AltName: Full=Ethylene-responsive element-binding factor 15;
DE            Short=EREBP-15;
GN   Name=ERF15; Synonyms=ERF-15, ERF093; OrderedLocusNames=At2g31230;
GN   ORFNames=F16D14.7;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   FUNCTION, AND INDUCTION.
RX   PubMed=11950980; DOI=10.1104/pp.010862;
RA   Onate-Sanchez L., Singh K.B.;
RT   "Identification of Arabidopsis ethylene-responsive element binding factors
RT   with distinct induction kinetics after pathogen infection.";
RL   Plant Physiol. 128:1313-1322(2002).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16407444; DOI=10.1104/pp.105.073783;
RA   Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT   "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL   Plant Physiol. 140:411-432(2006).
CC   -!- FUNCTION: May act as a transcriptional activator. Binds to the GCC-box
CC       pathogenesis-related promoter element. Involved in the regulation of
CC       gene expression by stress factors and by components of stress signal
CC       transduction pathways (By similarity). {ECO:0000250,
CC       ECO:0000269|PubMed:11950980}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- INDUCTION: Weakly induced by Pseudomonas syringae tomato (avirulent
CC       avrRpt2 strain), but also by mock inoculation.
CC       {ECO:0000269|PubMed:11950980}.
CC   -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC       subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD20668.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC006593; AAD20668.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC08512.1; -; Genomic_DNA.
DR   EMBL; AY070443; AAL49846.1; -; mRNA.
DR   EMBL; AY096563; AAM20213.1; -; mRNA.
DR   PIR; B84718; B84718.
DR   RefSeq; NP_850162.1; NM_179831.2.
DR   AlphaFoldDB; Q8VYM0; -.
DR   SMR; Q8VYM0; -.
DR   BioGRID; 3028; 1.
DR   STRING; 3702.AT2G31230.1; -.
DR   PaxDb; Q8VYM0; -.
DR   PRIDE; Q8VYM0; -.
DR   EnsemblPlants; AT2G31230.1; AT2G31230.1; AT2G31230.
DR   GeneID; 817680; -.
DR   Gramene; AT2G31230.1; AT2G31230.1; AT2G31230.
DR   KEGG; ath:AT2G31230; -.
DR   Araport; AT2G31230; -.
DR   TAIR; locus:2042496; AT2G31230.
DR   eggNOG; ENOG502RBAX; Eukaryota.
DR   HOGENOM; CLU_058713_1_1_1; -.
DR   InParanoid; Q8VYM0; -.
DR   OMA; LWNESCF; -.
DR   OrthoDB; 1363724at2759; -.
DR   PhylomeDB; Q8VYM0; -.
DR   PRO; PR:Q8VYM0; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q8VYM0; baseline and differential.
DR   Genevisible; Q8VYM0; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0009873; P:ethylene-activated signaling pathway; TAS:TAIR.
DR   CDD; cd00018; AP2; 1.
DR   Gene3D; 3.30.730.10; -; 1.
DR   InterPro; IPR001471; AP2/ERF_dom.
DR   InterPro; IPR036955; AP2/ERF_dom_sf.
DR   InterPro; IPR016177; DNA-bd_dom_sf.
DR   InterPro; IPR044808; ERF_plant.
DR   PANTHER; PTHR31190; PTHR31190; 1.
DR   Pfam; PF00847; AP2; 1.
DR   PRINTS; PR00367; ETHRSPELEMNT.
DR   SMART; SM00380; AP2; 1.
DR   SUPFAM; SSF54171; SSF54171; 1.
DR   PROSITE; PS51032; AP2_ERF; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Ethylene signaling pathway; Nucleus; Plant defense;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..243
FT                   /note="Ethylene-responsive transcription factor 15"
FT                   /id="PRO_0000112551"
FT   DNA_BIND        85..143
FT                   /note="AP2/ERF"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT   REGION          157..220
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           170..186
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        184..220
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   243 AA;  27056 MW;  E270B124831B7BBB CRC64;
     MEYSQSSMYS SPSSWSSSQE SLLWNESCFL DQSSEPQAFF CPNYDYSDDF FSFESPEMMI
     KEEIQNGDVS NSEEEEKVGI DEERSYRGVR KRPWGKFAAE IRDSTRNGIR VWLGTFDKAE
     EAALAYDQAA FATKGSLATL NFPVEVVRES LKKMENVNLH DGGSPVMALK RKHSLRNRPR
     GKKRSSSSSS SSSNSSSCSS SSSTSSTSRS SSKQSVVKQE SGTLVVFEDL GAEYLEQLLM
     SSC