位置:首页 > 蛋白库 > ERFD_CANAL
ERFD_CANAL
ID   ERFD_CANAL              Reviewed;         218 AA.
AC   Q5A1U8; A0A1D8PN33; Q5A1P1;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2017, sequence version 3.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Ras modification protein ERF4;
GN   Name=ERF4; Synonyms=SHR5; OrderedLocusNames=CAALFM_C501170WA;
GN   ORFNames=CaO19.1955, CaO19.9510;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: The ERF2-ERF4 complex is a palmitoyltransferase specific for
CC       Ras proteins. Palmitoylates RAS2, which is required for its proper
CC       plasma membrane localization (By similarity).
CC       {ECO:0000250|UniProtKB:P41912}.
CC   -!- SUBUNIT: Interacts with ERF2. {ECO:0000250|UniProtKB:P41912}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000250|UniProtKB:P41912}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:P41912}.
CC   -!- SIMILARITY: Belongs to the ERF4 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP017627; AOW29552.1; -; Genomic_DNA.
DR   RefSeq; XP_019330955.1; XM_019475410.1.
DR   AlphaFoldDB; Q5A1U8; -.
DR   STRING; 237561.Q5A1U8; -.
DR   GeneID; 3642662; -.
DR   KEGG; cal:CAALFM_C501170WA; -.
DR   CGD; CAL0000178317; orf19.9510.
DR   VEuPathDB; FungiDB:C5_01170W_A; -.
DR   eggNOG; ENOG502S30T; Eukaryota.
DR   HOGENOM; CLU_087349_0_0_1; -.
DR   InParanoid; Q5A1U8; -.
DR   OMA; CITHFPN; -.
DR   OrthoDB; 1305531at2759; -.
DR   PRO; PR:Q5A1U8; -.
DR   Proteomes; UP000000559; Chromosome 5.
DR   GO; GO:0031211; C:endoplasmic reticulum palmitoyltransferase complex; IBA:GO_Central.
DR   GO; GO:0042406; C:extrinsic component of endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0002178; C:palmitoyltransferase complex; IBA:GO_Central.
DR   GO; GO:0018230; P:peptidyl-L-cysteine S-palmitoylation; IBA:GO_Central.
DR   GO; GO:0006612; P:protein targeting to membrane; IBA:GO_Central.
DR   InterPro; IPR019383; Golgin_A_7/ERF4.
DR   Pfam; PF10256; Erf4; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Reference proteome.
FT   CHAIN           1..218
FT                   /note="Ras modification protein ERF4"
FT                   /id="PRO_0000213982"
SQ   SEQUENCE   218 AA;  24666 MW;  3AD6A1566D1DD8F8 CRC64;
     MNETKTDSTV NPDQSSQELV FFNYHEYLVP GSDDTSLVIN HFPNIHTDLS SSTFKETRII
     RIPRVYHTVQ FPDLIPQFSC YYPGSEPGAI TSTQLMSGSF DDNSFNESSS IPSLENIISR
     SEFENIVSLV NESLAVAFNP MSKRMLLENL LDLLSGGLFL SLLNFLGIYS FTKRKLMELE
     SQIDSINQIN EKKGVDFKII SPRVTGYLSL DFQITKPR
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2025