ERFL1_ARATH
ID ERFL1_ARATH Reviewed; 226 AA.
AC Q56XP9; Q9SV65;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 2.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=Ethylene-responsive transcription factor-like protein At4g13040;
GN OrderedLocusNames=At4g13040; ORFNames=F25G13.130;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 31-226 (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Probably acts as a transcriptional activator. Binds to the
CC GCC-box pathogenesis-related promoter element. May be involved in the
CC regulation of gene expression by stress factors and by components of
CC stress signal transduction pathways (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q56XP9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q56XP9-2; Sequence=VSP_026152, VSP_026153;
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB45503.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB78346.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL079349; CAB45503.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161535; CAB78346.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE83221.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE83222.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM67421.1; -; Genomic_DNA.
DR EMBL; AK221624; BAD95239.1; -; mRNA.
DR EMBL; AY133690; AAM91624.1; -; mRNA.
DR PIR; T10206; T10206.
DR RefSeq; NP_001078381.1; NM_001084912.2. [Q56XP9-2]
DR RefSeq; NP_001329251.1; NM_001340827.1.
DR RefSeq; NP_001329253.1; NM_001340829.1. [Q56XP9-2]
DR RefSeq; NP_001329254.1; NM_001340831.1.
DR RefSeq; NP_193040.2; NM_117373.5. [Q56XP9-1]
DR AlphaFoldDB; Q56XP9; -.
DR SMR; Q56XP9; -.
DR BioGRID; 12215; 4.
DR IntAct; Q56XP9; 2.
DR STRING; 3702.AT4G13040.3; -.
DR iPTMnet; Q56XP9; -.
DR PaxDb; Q56XP9; -.
DR PRIDE; Q56XP9; -.
DR ProteomicsDB; 220570; -. [Q56XP9-1]
DR EnsemblPlants; AT4G13040.1; AT4G13040.1; AT4G13040. [Q56XP9-1]
DR EnsemblPlants; AT4G13040.2; AT4G13040.2; AT4G13040. [Q56XP9-2]
DR EnsemblPlants; AT4G13040.6; AT4G13040.6; AT4G13040. [Q56XP9-2]
DR GeneID; 826918; -.
DR Gramene; AT4G13040.1; AT4G13040.1; AT4G13040. [Q56XP9-1]
DR Gramene; AT4G13040.2; AT4G13040.2; AT4G13040. [Q56XP9-2]
DR Gramene; AT4G13040.6; AT4G13040.6; AT4G13040. [Q56XP9-2]
DR KEGG; ath:AT4G13040; -.
DR Araport; AT4G13040; -.
DR eggNOG; ENOG502QV4T; Eukaryota.
DR HOGENOM; CLU_088368_0_0_1; -.
DR InParanoid; Q56XP9; -.
DR OMA; PRFFDNG; -.
DR PhylomeDB; Q56XP9; -.
DR PRO; PR:Q56XP9; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q56XP9; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 1.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 2: Evidence at transcript level;
KW Activator; Alternative splicing; DNA-binding; Ethylene signaling pathway;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..226
FT /note="Ethylene-responsive transcription factor-like
FT protein At4g13040"
FT /id="PRO_0000290437"
FT DNA_BIND 105..171
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 63..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..79
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..56
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_026152"
FT VAR_SEQ 57..95
FT /note="VEKKAIEERSRRTRSKHMHFRSDYSDISPVNSDSISPKY -> MPEQLIIPG
FT QQKRLQRLSWRKRLLKKEAEELGQNICISD (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_026153"
FT CONFLICT 180
FT /note="S -> T (in Ref. 1; BAD95239)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 226 AA; 26400 MW; 7BF8D450D7562497 CRC64;
MVSLRRRRLL GLCCGPNGYV TPLPFLTAEE MITGIPNPNA RAAYNPGPAE TVTTVIVEKK
AIEERSRRTR SKHMHFRSDY SDISPVNSDS ISPKYQPPKR RKQHRRKRVH NQEPCLMRGV
YYKNMKWQAA IKVEKKQIHL GTFSSQEEAA RLYDRAAFMC GREPNFELSE EVIRELKQQS
WEEFLNCTRR TITNKKPKSR IEHEDTKINA SMPHQPEEEE QDSDKM
