ID   ERG28_PONAB             Reviewed;         140 AA.
AC   Q5R589;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Ergosterol biosynthetic protein 28 homolog;
GN   Name=ERG28;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ERG28 family. {ECO:0000305}.
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DR   EMBL; CR860975; CAH93077.1; -; mRNA.
DR   RefSeq; NP_001128964.1; NM_001135492.1.
DR   AlphaFoldDB; Q5R589; -.
DR   STRING; 9601.ENSPPYP00000006832; -.
DR   Ensembl; ENSPPYT00000007101; ENSPPYP00000006832; ENSPPYG00000006007.
DR   GeneID; 100190804; -.
DR   KEGG; pon:100190804; -.
DR   CTD; 11161; -.
DR   eggNOG; KOG3455; Eukaryota.
DR   GeneTree; ENSGT00390000010925; -.
DR   HOGENOM; CLU_114589_2_0_1; -.
DR   InParanoid; Q5R589; -.
DR   OMA; SEWLIFG; -.
DR   OrthoDB; 1590576at2759; -.
DR   TreeFam; TF300191; -.
DR   Proteomes; UP000001595; Chromosome 14.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030133; C:transport vesicle; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR005352; Erg28.
DR   PANTHER; PTHR15451; PTHR15451; 1.
DR   Pfam; PF03694; Erg28; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Lipid biosynthesis; Lipid metabolism; Membrane;
KW   Reference proteome; Steroid biosynthesis; Steroid metabolism;
KW   Sterol biosynthesis; Sterol metabolism; Transmembrane; Transmembrane helix.
FT   CHAIN           1..140
FT                   /note="Ergosterol biosynthetic protein 28 homolog"
FT                   /id="PRO_0000193905"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   140 AA;  15864 MW;  BDD089148BC60E50 CRC64;
     MSRFLNVLRS WLVMVSIIAM GNTLQSFRDH TFLYEKLYTG KPNLVNGLQA RTFGIWTLLS
     SVIRCLCAID IHNKTLYHIT LWTFLLALGH FLSELFVYGT AAPTIGVLAP LMVASFSILG
     MLVGLRYLEV EPVSRQKKRN