ID   ERG_ANTMA               Reviewed;         423 AA.
AC   O82626;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=GTP-binding protein ERG;
GN   Name=ERG;
OS   Antirrhinum majus (Garden snapdragon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Lamiales; Plantaginaceae; Antirrhineae; Antirrhinum.
OX   NCBI_TaxID=4151;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=9768362; DOI=10.1016/s0960-9822(98)70445-2;
RA   Ingram G.C., Simon R., Carpenter R., Coen E.S.;
RT   "The Antirrhinum ERG gene encodes a protein related to bacterial small
RT   GTPases and is required for embryonic viability.";
RL   Curr. Biol. 8:1079-1082(1998).
CC   -!- FUNCTION: Has a crucial role in plant growth and development, possibly
CC       by influencing mitochondrial division.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. Era GTPase family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01050, ECO:0000305}.
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DR   EMBL; Y17899; CAA76925.1; -; mRNA.
DR   AlphaFoldDB; O82626; -.
DR   SMR; O82626; -.
DR   PRIDE; O82626; -.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   CDD; cd04163; Era; 1.
DR   Gene3D; 3.30.300.20; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00367; GTPase_Era; 1.
DR   InterPro; IPR030388; G_ERA_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR005662; GTP-bd_Era.
DR   InterPro; IPR015946; KH_dom-like_a/b.
DR   InterPro; IPR004044; KH_dom_type_2.
DR   InterPro; IPR009019; KH_sf_prok-type.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   PANTHER; PTHR42698; PTHR42698; 1.
DR   Pfam; PF07650; KH_2; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54814; SSF54814; 1.
DR   TIGRFAMs; TIGR00436; era; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51713; G_ERA; 1.
DR   PROSITE; PS50823; KH_TYPE_2; 1.
PE   2: Evidence at transcript level;
KW   GTP-binding; Nucleotide-binding; RNA-binding.
FT   CHAIN           1..423
FT                   /note="GTP-binding protein ERG"
FT                   /id="PRO_0000180079"
FT   DOMAIN          138..316
FT                   /note="Era-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01050"
FT   DOMAIN          347..423
FT                   /note="KH type-2"
FT   REGION          146..153
FT                   /note="G1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01050"
FT   REGION          172..176
FT                   /note="G2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01050"
FT   REGION          193..196
FT                   /note="G3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01050"
FT   REGION          265..268
FT                   /note="G4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01050"
FT   REGION          295..297
FT                   /note="G5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01050"
FT   BINDING         146..153
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255"
FT   BINDING         193..197
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255"
FT   BINDING         265..268
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   423 AA;  48142 MW;  9A71F436AA62A527 CRC64;
     MKAVRAALRL RPLTNSISTS VYLHRFYSAQ PQHTDDEHHP KPEELLHQSD AVFDSSHFDL
     DLNNLAASGA ETTTWDERYR DRVKSRVFDE DDTSSYSKIL KRDEEKKYKS AALAKSLLEA
     ALDDEEVEVG EVKEEDQKSL SVGIIGAPNA GKSALTNYIV GTKVSAVSRK TNTTTHEVLG
     VLTKRDTQIC FFDTPGLMLK KSGIPYNDIK VRNESGWSSI TLYDVLIVIF DVHRHLTRPD
     SRVVRLIERV GSVSSTSQKR VLCMNKVDLV TKKNDLVKVA KEFKDLPGYE RHFMVSGLKG
     YGLKDLAQYL TEQAVKRPWD EDPFAMSEEV MKNISLEVVR EKLLDYVHQE IPYGIEHRLM
     GWKELRDGSL RIEQHFITPK MSQRKILVGK KGSKIGTIGI EANEELRSIF KRNVHLILMV
     KVK