ID   ERG_LYTVA               Reviewed;         173 AA.
AC   Q01414;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Transcriptional regulator ERG homolog;
DE   Flags: Fragment;
GN   Name=ERG;
OS   Lytechinus variegatus (Green sea urchin) (Echinus variegatus).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Temnopleuroida; Toxopneustidae; Lytechinus.
OX   NCBI_TaxID=7654;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1457815; DOI=10.3109/10425179209034008;
RA   Qi S., Chen Z.Q., Papas T.S., Lautenberger J.A.;
RT   "The sea urchin erg homolog defines a highly conserved erg-specific
RT   domain.";
RL   DNA Seq. 3:127-129(1992).
CC   -!- FUNCTION: Acts as a transcriptional activator.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SIMILARITY: Belongs to the ETS family. {ECO:0000305}.
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DR   EMBL; M81067; AAA68905.1; -; Genomic_DNA.
DR   PIR; A56646; A56646.
DR   AlphaFoldDB; Q01414; -.
DR   SMR; Q01414; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR046328; ETS_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849; PTHR11849; 1.
DR   Pfam; PF00178; Ets; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           <1..173
FT                   /note="Transcriptional regulator ERG homolog"
FT                   /id="PRO_0000204106"
FT   DNA_BIND        <1..84
FT                   /note="ETS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00237"
FT   NON_TER         1
SQ   SEQUENCE   173 AA;  19690 MW;  F85D496DD58A8F3D CRC64;
     SGQIQLWQFL LELLSDSSNA NCITWEGTNG EFKMTDPDEV ARRWGERKSK PNMNYDKLSR
     ALRYYYDKNI MTKVHGKRYA YKFDFAGLAQ AMQPVQADPS MYRYQSDLTY LPGYHPTKLN
     FVGTPINPST NASLFSSHSS YWSSPTGANI YPSGHVTHPH ASHMSSHIGT YYG