ID   ERH_AEDAE               Reviewed;         103 AA.
AC   Q93104;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Enhancer of rudimentary homolog;
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
RX   PubMed=9074495; DOI=10.1016/s0378-1119(96)00701-9;
RA   Gelsthorpe M., Pulumati M., McCallum C., Dang-Vu K., Tsubota S.I.;
RT   "The putative cell cycle gene, enhancer of rudimentary, encodes a highly
RT   conserved protein found in plants and animals.";
RL   Gene 186:189-195(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LVPib12;
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA   Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA   Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA   Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA   Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA   El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA   Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA   Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA   Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA   Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA   Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA   Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA   Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
CC   -!- FUNCTION: May have a role in the cell cycle.
CC       {ECO:0000269|PubMed:9074495}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the E(R) family. {ECO:0000305}.
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DR   EMBL; U66869; AAC47489.1; -; mRNA.
DR   EMBL; CH477756; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; Q93104; -.
DR   SMR; Q93104; -.
DR   VEuPathDB; VectorBase:AAEL021736; -.
DR   Proteomes; UP000008820; Chromosome 1.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.2260.10; -; 1.
DR   InterPro; IPR035912; EHR_sf.
DR   InterPro; IPR000781; ERH.
DR   PANTHER; PTHR12373; PTHR12373; 1.
DR   Pfam; PF01133; ER; 1.
DR   PIRSF; PIRSF016393; Enh_rudimentary; 1.
DR   SUPFAM; SSF143875; SSF143875; 1.
DR   PROSITE; PS01290; ER; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Reference proteome.
FT   CHAIN           1..103
FT                   /note="Enhancer of rudimentary homolog"
FT                   /id="PRO_0000219350"
SQ   SEQUENCE   103 AA;  12016 MW;  76DBC9A52040DB66 CRC64;
     MSHTILLVQP GRNPETRTYS DYESVNECME GVCKIYEEHL KRRNPNTPTI TYDISQLFDF
     VDQLADLSCL VYQKSTNTYA PYNKEWIKEK IYVLLRQAAG TTD