ERIC5_MOUSE
ID ERIC5_MOUSE Reviewed; 362 AA.
AC Q8K0S2; Q3TS52; Q3UX98;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Glutamate-rich protein 5;
GN Name=Erich5;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Eye, and Oocyte;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-341.
RC STRAIN=C57BL/6J;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-161, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Pancreas;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC030476; AAH30476.1; -; mRNA.
DR EMBL; BC099414; AAH99414.1; -; mRNA.
DR EMBL; AK135792; BAE22665.1; -; mRNA.
DR EMBL; AK162262; BAE36823.1; -; mRNA.
DR CCDS; CCDS27417.1; -.
DR RefSeq; NP_775597.1; NM_173421.2.
DR AlphaFoldDB; Q8K0S2; -.
DR STRING; 10090.ENSMUSP00000058182; -.
DR iPTMnet; Q8K0S2; -.
DR PhosphoSitePlus; Q8K0S2; -.
DR MaxQB; Q8K0S2; -.
DR PaxDb; Q8K0S2; -.
DR PRIDE; Q8K0S2; -.
DR ProteomicsDB; 275471; -.
DR Antibodypedia; 13018; 62 antibodies from 9 providers.
DR DNASU; 239368; -.
DR Ensembl; ENSMUST00000060894; ENSMUSP00000058182; ENSMUSG00000044726.
DR GeneID; 239368; -.
DR KEGG; mmu:239368; -.
DR UCSC; uc007vls.2; mouse.
DR CTD; 203111; -.
DR MGI; MGI:2447772; Erich5.
DR VEuPathDB; HostDB:ENSMUSG00000044726; -.
DR eggNOG; ENOG502SVIU; Eukaryota.
DR GeneTree; ENSGT00390000010783; -.
DR HOGENOM; CLU_064315_0_0_1; -.
DR InParanoid; Q8K0S2; -.
DR OMA; MNDPLHK; -.
DR OrthoDB; 962254at2759; -.
DR PhylomeDB; Q8K0S2; -.
DR TreeFam; TF337219; -.
DR BioGRID-ORCS; 239368; 3 hits in 71 CRISPR screens.
DR ChiTaRS; Erich5; mouse.
DR PRO; PR:Q8K0S2; -.
DR Proteomes; UP000000589; Chromosome 15.
DR RNAct; Q8K0S2; protein.
DR Bgee; ENSMUSG00000044726; Expressed in animal zygote and 20 other tissues.
DR InterPro; IPR027856; DUF4573.
DR Pfam; PF15140; DUF4573; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..362
FT /note="Glutamate-rich protein 5"
FT /id="PRO_0000294434"
FT REGION 1..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 183..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..156
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..349
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 161
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
SQ SEQUENCE 362 AA; 38527 MW; 0F42E85A8388E5C7 CRC64;
MGCSSSALNK AGDSSRFGSG VTSNENSSTV EHNKFCVDQP KPCTPGGEAA FHGNTQRESH
PSLERPKASV VPTANGVKSY HQPSLANDET PGKEATDHSR PTKKIEPLVQ GGECEQPQPG
GKDDMLGTEE VKKDVEARTE VPSLKGDAEI KPLRLSSERD SPGAPQAGTM KFLQTAENIL
PLETTQELPP KEATGKGAQP QILEAIPKEN SSPEIEGIQS AESSGQQQLV EAPGEAEQPQ
ALETVLKENE TSQMPGRSQP VPTPVMNKSP CEAPDGLRNA HEPQVTGGNR VQPAETGETA
AKVEMAREIH PDKEEQHIEG ETGEKVEAEM KNEKESEEAE TKEKETGEAV DLGAAGAGDR
RA
