ID   ERIP6_MOUSE             Reviewed;         713 AA.
AC   D3Z6S9;
DT   15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Glutamate-rich protein 6;
DE   AltName: Full=Protein FAM194A;
GN   Name=Erich6; Synonyms=Fam194a;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
CC   -!- SIMILARITY: Belongs to the ERICH6 family. {ECO:0000305}.
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DR   EMBL; AC119873; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS50914.1; -.
DR   RefSeq; NP_001074731.1; NM_001081262.1.
DR   AlphaFoldDB; D3Z6S9; -.
DR   BioGRID; 244381; 1.
DR   STRING; 10090.ENSMUSP00000040882; -.
DR   iPTMnet; D3Z6S9; -.
DR   PhosphoSitePlus; D3Z6S9; -.
DR   PaxDb; D3Z6S9; -.
DR   PRIDE; D3Z6S9; -.
DR   ProteomicsDB; 275885; -.
DR   Antibodypedia; 62352; 15 antibodies from 7 providers.
DR   Ensembl; ENSMUST00000041115; ENSMUSP00000040882; ENSMUSG00000070471.
DR   GeneID; 545527; -.
DR   KEGG; mmu:545527; -.
DR   UCSC; uc008phy.1; mouse.
DR   CTD; 131831; -.
DR   MGI; MGI:3588212; Erich6.
DR   VEuPathDB; HostDB:ENSMUSG00000070471; -.
DR   eggNOG; ENOG502QUAE; Eukaryota.
DR   GeneTree; ENSGT00940000153655; -.
DR   HOGENOM; CLU_030265_0_0_1; -.
DR   InParanoid; D3Z6S9; -.
DR   OMA; ENWVINP; -.
DR   OrthoDB; 866189at2759; -.
DR   PhylomeDB; D3Z6S9; -.
DR   TreeFam; TF333451; -.
DR   BioGRID-ORCS; 545527; 6 hits in 73 CRISPR screens.
DR   PRO; PR:D3Z6S9; -.
DR   Proteomes; UP000000589; Chromosome 3.
DR   RNAct; D3Z6S9; protein.
DR   Bgee; ENSMUSG00000070471; Expressed in seminiferous tubule of testis and 50 other tissues.
DR   Genevisible; D3Z6S9; MM.
DR   InterPro; IPR029281; FAM194_C.
DR   Pfam; PF14977; FAM194; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..713
FT                   /note="Glutamate-rich protein 6"
FT                   /id="PRO_0000395103"
FT   REGION          1..177
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..20
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..45
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        46..69
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        112..126
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        132..148
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   713 AA;  80949 MW;  64DD9F6BD5460AF4 CRC64;
     MRPRQGVRKP GKRNTKSKKP DKASKGKEMV EAEKAQKMQR EQGEELEQEG QEEEVEEEEK
     EEEAKEEQGA QEEQEGQGAQ GVQGWDDREG QPQESQNLFP ESLNEEDIWK AIGPSEGFDE
     DSPEFRPRLI SVVSPSLSTM SPPSKVSSPS WGEEEPLPLP HREGSPPASS SGSSHKSYPK
     IFQTFKKDLS EVTVDRDMYP SLYERVQMSV QTEDESWLQR ISAKKQIKRI PSIEITETLP
     QTQASMLREN WVINPEEPKL SILCEMEFNE DFVNLFETSL RTLPSVGPPA ILSFRKEYSY
     MDVNFKDEQE LEPTCEFCGS DLRSLFFKMD TSSENIQTKP KSYRCCCLQF QNLLDYINEE
     MLTIKPPALE LISISPHAAY GSDIDRLKAK EKALQKKQER QMARHFAIIS HDQSPTTTDD
     GKTFVTDALE IQKTYSQNSI TQREAGNILK YSFPCSAFPS WLNFTCEQSV CTDLIHTEMR
     CSVYFGFDAS VDGTILLTYP SGNLAIIRLP NKTDGFICII QEDTPTNPTI LALFDSSGRS
     SCYHPNGNVW VYINILGGQY SDQAGNRIRT WNWSSTMPSS SFVSFKPVFL ALNRYIGIRI
     LEQDKVSINF LAMGQQATIS LGTKVMLHDP EEVPALWFLS GDDLLLLANL IKIRRLFNKL
     EGCMNFPISQ AWEKLKQPPY LSSLSLKLLA LCHNSGIQQK TMETIIDLIK EEE