ID   ERPA2_BURVG             Reviewed;         124 AA.
AC   A4JRL3;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Putative iron-sulfur cluster insertion protein ErpA 2 {ECO:0000255|HAMAP-Rule:MF_01380};
GN   Name=erpA2 {ECO:0000255|HAMAP-Rule:MF_01380};
GN   OrderedLocusNames=Bcep1808_5991;
OS   Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia
OS   (strain R1808)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=269482;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G4 / LMG 22486;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 3 of Burkholderia vietnamiensis G4.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for insertion of 4Fe-4S clusters.
CC       {ECO:0000255|HAMAP-Rule:MF_01380}.
CC   -!- COFACTOR:
CC       Name=iron-sulfur cluster; Xref=ChEBI:CHEBI:30408;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01380};
CC       Note=Binds 1 iron-sulfur cluster per subunit. {ECO:0000255|HAMAP-
CC       Rule:MF_01380};
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01380}.
CC   -!- SIMILARITY: Belongs to the HesB/IscA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01380}.
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DR   EMBL; CP000616; ABO58916.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4JRL3; -.
DR   SMR; A4JRL3; -.
DR   STRING; 269482.Bcep1808_5991; -.
DR   EnsemblBacteria; ABO58916; ABO58916; Bcep1808_5991.
DR   KEGG; bvi:Bcep1808_5991; -.
DR   eggNOG; COG0316; Bacteria.
DR   HOGENOM; CLU_069054_5_3_4; -.
DR   OMA; MEYVEEA; -.
DR   Proteomes; UP000002287; Chromosome 3.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProt.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.60.300.12; -; 1.
DR   HAMAP; MF_01380; Fe_S_insert_ErpA; 1.
DR   InterPro; IPR000361; FeS_biogenesis.
DR   InterPro; IPR016092; FeS_cluster_insertion.
DR   InterPro; IPR017870; FeS_cluster_insertion_CS.
DR   InterPro; IPR023063; FeS_cluster_insertion_RrpA.
DR   InterPro; IPR035903; HesB-like_dom_sf.
DR   Pfam; PF01521; Fe-S_biosyn; 1.
DR   SUPFAM; SSF89360; SSF89360; 1.
DR   TIGRFAMs; TIGR00049; TIGR00049; 1.
DR   PROSITE; PS01152; HESB; 1.
PE   3: Inferred from homology;
KW   Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT   CHAIN           1..124
FT                   /note="Putative iron-sulfur cluster insertion protein ErpA
FT                   2"
FT                   /id="PRO_0000311468"
FT   BINDING         52
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
FT   BINDING         116
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
FT   BINDING         118
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
SQ   SEQUENCE   124 AA;  13025 MW;  B9BBCE868CFED3A0 CRC64;
     MELLQPSADA APVPLPAFLD FTPNAAAKVA ALIDAEGNPQ LKLRLYVSGG GCSGFQYGFA
     FDDQVADDDL QVVTDGVTLL IDAMSRQYLA GARVDYEDGL EGSRFVIQNP NAQSTCGCGS
     SFSV