ERPA_ALISL
ID ERPA_ALISL Reviewed; 113 AA.
AC B6EL03;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 25-NOV-2008, sequence version 1.
DT 03-AUG-2022, entry version 62.
DE RecName: Full=Iron-sulfur cluster insertion protein ErpA {ECO:0000255|HAMAP-Rule:MF_01380};
GN Name=erpA {ECO:0000255|HAMAP-Rule:MF_01380}; OrderedLocusNames=VSAL_I2571;
OS Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain
OS LFI1238)).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Aliivibrio.
OX NCBI_TaxID=316275;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LFI1238;
RX PubMed=19099551; DOI=10.1186/1471-2164-9-616;
RA Hjerde E., Lorentzen M.S., Holden M.T., Seeger K., Paulsen S., Bason N.,
RA Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S.,
RA Thurston S., Parkhill J., Willassen N.P., Thomson N.R.;
RT "The genome sequence of the fish pathogen Aliivibrio salmonicida strain
RT LFI1238 shows extensive evidence of gene decay.";
RL BMC Genomics 9:616-616(2008).
CC -!- FUNCTION: Required for insertion of 4Fe-4S clusters for at least IspG.
CC {ECO:0000255|HAMAP-Rule:MF_01380}.
CC -!- COFACTOR:
CC Name=iron-sulfur cluster; Xref=ChEBI:CHEBI:30408;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01380};
CC Note=Binds 1 iron-sulfur cluster per subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01380};
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01380}.
CC -!- SIMILARITY: Belongs to the HesB/IscA family. {ECO:0000255|HAMAP-
CC Rule:MF_01380}.
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DR EMBL; FM178379; CAQ80255.1; -; Genomic_DNA.
DR RefSeq; WP_012551041.1; NC_011312.1.
DR AlphaFoldDB; B6EL03; -.
DR SMR; B6EL03; -.
DR STRING; 316275.VSAL_I2571; -.
DR EnsemblBacteria; CAQ80255; CAQ80255; VSAL_I2571.
DR KEGG; vsa:VSAL_I2571; -.
DR eggNOG; COG0316; Bacteria.
DR HOGENOM; CLU_069054_5_3_6; -.
DR OMA; YQLYFDE; -.
DR OrthoDB; 1891602at2; -.
DR Proteomes; UP000001730; Chromosome 1.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProt.
DR GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.300.12; -; 1.
DR HAMAP; MF_01380; Fe_S_insert_ErpA; 1.
DR InterPro; IPR000361; FeS_biogenesis.
DR InterPro; IPR016092; FeS_cluster_insertion.
DR InterPro; IPR017870; FeS_cluster_insertion_CS.
DR InterPro; IPR023063; FeS_cluster_insertion_RrpA.
DR InterPro; IPR035903; HesB-like_dom_sf.
DR Pfam; PF01521; Fe-S_biosyn; 1.
DR SUPFAM; SSF89360; SSF89360; 1.
DR TIGRFAMs; TIGR00049; TIGR00049; 1.
DR PROSITE; PS01152; HESB; 1.
PE 3: Inferred from homology;
KW Iron; Iron-sulfur; Metal-binding.
FT CHAIN 1..113
FT /note="Iron-sulfur cluster insertion protein ErpA"
FT /id="PRO_1000144894"
FT BINDING 41
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
FT BINDING 105
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
FT BINDING 107
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
SQ SEQUENCE 113 AA; 12032 MW; E44C547B6F4A6577 CRC64;
MSDVSVPLTF SDVAAAKVKT LIAEEENPNL KLRVYITGGG CSGFQYGFTF DEEVNEGDMT
LVNDGVTLVV DPMSLQYLIG GIVDYTEGLE GSRFFINNPN ATTTCGCGAS FSV
