ID   ERPA_BUCAI              Reviewed;         114 AA.
AC   P57307;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Iron-sulfur cluster insertion protein ErpA {ECO:0000255|HAMAP-Rule:MF_01380};
GN   Name=erpA {ECO:0000255|HAMAP-Rule:MF_01380}; OrderedLocusNames=BU211;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- FUNCTION: Required for insertion of 4Fe-4S clusters for at least IspG.
CC       {ECO:0000255|HAMAP-Rule:MF_01380}.
CC   -!- COFACTOR:
CC       Name=iron-sulfur cluster; Xref=ChEBI:CHEBI:30408;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01380};
CC       Note=Binds 1 iron-sulfur cluster per subunit. {ECO:0000255|HAMAP-
CC       Rule:MF_01380};
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01380}.
CC   -!- SIMILARITY: Belongs to the HesB/IscA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01380}.
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DR   EMBL; BA000003; BAB12928.1; -; Genomic_DNA.
DR   RefSeq; NP_240042.1; NC_002528.1.
DR   RefSeq; WP_010896006.1; NC_002528.1.
DR   AlphaFoldDB; P57307; -.
DR   SMR; P57307; -.
DR   STRING; 107806.10038893; -.
DR   EnsemblBacteria; BAB12928; BAB12928; BAB12928.
DR   KEGG; buc:BU211; -.
DR   PATRIC; fig|107806.10.peg.223; -.
DR   eggNOG; COG0316; Bacteria.
DR   HOGENOM; CLU_069054_5_3_6; -.
DR   OMA; YQLYFDE; -.
DR   Proteomes; UP000001806; Chromosome.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProt.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.60.300.12; -; 1.
DR   HAMAP; MF_01380; Fe_S_insert_ErpA; 1.
DR   InterPro; IPR000361; FeS_biogenesis.
DR   InterPro; IPR016092; FeS_cluster_insertion.
DR   InterPro; IPR017870; FeS_cluster_insertion_CS.
DR   InterPro; IPR023063; FeS_cluster_insertion_RrpA.
DR   InterPro; IPR035903; HesB-like_dom_sf.
DR   Pfam; PF01521; Fe-S_biosyn; 1.
DR   SUPFAM; SSF89360; SSF89360; 1.
DR   TIGRFAMs; TIGR00049; TIGR00049; 1.
DR   PROSITE; PS01152; HESB; 1.
PE   3: Inferred from homology;
KW   Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT   CHAIN           1..114
FT                   /note="Iron-sulfur cluster insertion protein ErpA"
FT                   /id="PRO_0000077015"
FT   BINDING         42
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
FT   BINDING         106
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
FT   BINDING         108
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
SQ   SEQUENCE   114 AA;  12908 MW;  50B5B9F1FE45A1CB CRC64;
     MENAFKSHLQ FTEKAIKKIK NLIEIEKNHD LKLRIYINGG GCSGFQYQFI FDTSINEDDI
     IITQSEVSLI IDPISLQYLY GGQIDYLENL EGSKFIVYNP NAKNTCGCGS SFSI