ID   ERPA_NITMU              Reviewed;         127 AA.
AC   Q2YBK7;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 2.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Putative iron-sulfur cluster insertion protein ErpA {ECO:0000255|HAMAP-Rule:MF_01380};
GN   Name=erpA {ECO:0000255|HAMAP-Rule:MF_01380}; OrderedLocusNames=Nmul_A0556;
OS   Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosospira.
OX   NCBI_TaxID=323848;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25196 / NCIMB 11849 / C 71;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC
RT   25196.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for insertion of 4Fe-4S clusters.
CC       {ECO:0000255|HAMAP-Rule:MF_01380}.
CC   -!- COFACTOR:
CC       Name=iron-sulfur cluster; Xref=ChEBI:CHEBI:30408;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01380};
CC       Note=Binds 1 iron-sulfur cluster per subunit. {ECO:0000255|HAMAP-
CC       Rule:MF_01380};
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01380}.
CC   -!- SIMILARITY: Belongs to the HesB/IscA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01380}.
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DR   EMBL; CP000103; ABB73864.1; -; Genomic_DNA.
DR   RefSeq; WP_049783052.1; NZ_FNVK01000019.1.
DR   AlphaFoldDB; Q2YBK7; -.
DR   SMR; Q2YBK7; -.
DR   STRING; 323848.Nmul_A0556; -.
DR   EnsemblBacteria; ABB73864; ABB73864; Nmul_A0556.
DR   KEGG; nmu:Nmul_A0556; -.
DR   eggNOG; COG0316; Bacteria.
DR   HOGENOM; CLU_069054_5_3_4; -.
DR   OrthoDB; 1891602at2; -.
DR   Proteomes; UP000002718; Chromosome.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProt.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.60.300.12; -; 1.
DR   HAMAP; MF_01380; Fe_S_insert_ErpA; 1.
DR   InterPro; IPR000361; FeS_biogenesis.
DR   InterPro; IPR016092; FeS_cluster_insertion.
DR   InterPro; IPR023063; FeS_cluster_insertion_RrpA.
DR   InterPro; IPR035903; HesB-like_dom_sf.
DR   Pfam; PF01521; Fe-S_biosyn; 1.
DR   SUPFAM; SSF89360; SSF89360; 1.
DR   TIGRFAMs; TIGR00049; TIGR00049; 1.
PE   3: Inferred from homology;
KW   Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT   CHAIN           1..127
FT                   /note="Putative iron-sulfur cluster insertion protein ErpA"
FT                   /id="PRO_0000311514"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         55
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
FT   BINDING         119
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
FT   BINDING         121
FT                   /ligand="iron-sulfur cluster"
FT                   /ligand_id="ChEBI:CHEBI:30408"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
SQ   SEQUENCE   127 AA;  13621 MW;  B511F29299F92A07 CRC64;
     MNTPFNDGSG QTDPMTDIPT PLIFTDNAAN KVRELIEEEG NNDLKLRVFV AGGGCSGFKY
     GFTFDELISE DDTVMEKNGV KLLVDAMSFQ YLAGAEIDYQ ENAEGAQFII KNPGAASTCG
     CGSSFSV