ERPA_PECAS
ID ERPA_PECAS Reviewed; 115 AA.
AC Q6D1Z1;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Iron-sulfur cluster insertion protein ErpA {ECO:0000255|HAMAP-Rule:MF_01380};
GN Name=erpA {ECO:0000255|HAMAP-Rule:MF_01380}; OrderedLocusNames=ECA3306;
OS Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS carotovora subsp. atroseptica).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Pectobacterium.
OX NCBI_TaxID=218491;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCRI 1043 / ATCC BAA-672;
RX PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT subsp. atroseptica and characterization of virulence factors.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC -!- FUNCTION: Required for insertion of 4Fe-4S clusters for at least IspG.
CC {ECO:0000255|HAMAP-Rule:MF_01380}.
CC -!- COFACTOR:
CC Name=iron-sulfur cluster; Xref=ChEBI:CHEBI:30408;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01380};
CC Note=Binds 1 iron-sulfur cluster per subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01380};
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01380}.
CC -!- SIMILARITY: Belongs to the HesB/IscA family. {ECO:0000255|HAMAP-
CC Rule:MF_01380}.
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DR EMBL; BX950851; CAG76204.1; -; Genomic_DNA.
DR RefSeq; WP_005969047.1; NC_004547.2.
DR AlphaFoldDB; Q6D1Z1; -.
DR SMR; Q6D1Z1; -.
DR STRING; 218491.ECA3306; -.
DR EnsemblBacteria; CAG76204; CAG76204; ECA3306.
DR GeneID; 51390696; -.
DR GeneID; 61409105; -.
DR GeneID; 66801357; -.
DR KEGG; eca:ECA3306; -.
DR eggNOG; COG0316; Bacteria.
DR HOGENOM; CLU_069054_5_3_6; -.
DR OMA; YQLYFDE; -.
DR OrthoDB; 1891602at2; -.
DR Proteomes; UP000007966; Chromosome.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProt.
DR GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.300.12; -; 1.
DR HAMAP; MF_01380; Fe_S_insert_ErpA; 1.
DR InterPro; IPR000361; FeS_biogenesis.
DR InterPro; IPR016092; FeS_cluster_insertion.
DR InterPro; IPR017870; FeS_cluster_insertion_CS.
DR InterPro; IPR023063; FeS_cluster_insertion_RrpA.
DR InterPro; IPR035903; HesB-like_dom_sf.
DR Pfam; PF01521; Fe-S_biosyn; 1.
DR SUPFAM; SSF89360; SSF89360; 1.
DR TIGRFAMs; TIGR00049; TIGR00049; 1.
DR PROSITE; PS01152; HESB; 1.
PE 3: Inferred from homology;
KW Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT CHAIN 1..115
FT /note="Iron-sulfur cluster insertion protein ErpA"
FT /id="PRO_0000311477"
FT BINDING 43
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
FT BINDING 107
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
FT BINDING 109
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01380"
SQ SEQUENCE 115 AA; 12198 MW; 81711D04FA8194D0 CRC64;
MSDDIAALPL QFTDAAASKV KNLIADEENP ELKLRVYITG GGCSGFQYGF TFDDQINDGD
MTIEKQGVAL VVDPMSLQYL VGGAVDYTEG LEGSRFIVTN PNAKSTCGCG SSFSV
