ERS2_ORYSJ
ID ERS2_ORYSJ Reviewed; 635 AA.
AC Q0DKM0; Q5WMY2;
DT 16-SEP-2015, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Probable ethylene response sensor 2 {ECO:0000305};
DE Short=OsERS2 {ECO:0000303|PubMed:16891544};
DE EC=2.7.13.3 {ECO:0000305};
DE AltName: Full=Ethylene response factor 2 {ECO:0000303|PubMed:16891544};
GN Name=ERS2;
GN OrderedLocusNames=Os05g0155200 {ECO:0000312|EMBL:BAF16603.1},
GN LOC_Os05g06320 {ECO:0000305};
GN ORFNames=OsJ_17173 {ECO:0000312|EMBL:EEE62384.1},
GN P0431G05.6 {ECO:0000312|EMBL:AAV32219.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT "A fine physical map of the rice chromosome 5.";
RL Mol. Genet. Genomics 274:337-345(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP DISRUPTION PHENOTYPE.
RX PubMed=16891544; DOI=10.1104/pp.106.086371;
RA Pareek A., Singh A., Kumar M., Kushwaha H.R., Lynn A.M.,
RA Singla-Pareek S.L.;
RT "Whole-genome analysis of Oryza sativa reveals similar architecture of two-
RT component signaling machinery with Arabidopsis.";
RL Plant Physiol. 142:380-397(2006).
RN [8]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=19417056; DOI=10.1105/tpc.108.065391;
RA Wuriyanghan H., Zhang B., Cao W.H., Ma B., Lei G., Liu Y.F., Wei W.,
RA Wu H.J., Chen L.J., Chen H.W., Cao Y.R., He S.J., Zhang W.K., Wang X.J.,
RA Chen S.Y., Zhang J.S.;
RT "The ethylene receptor ETR2 delays floral transition and affects starch
RT accumulation in rice.";
RL Plant Cell 21:1473-1494(2009).
CC -!- FUNCTION: Ethylene receptor related to bacterial two-component
CC regulators. Acts as negative regulator of ethylene signaling. May play
CC a role in the regulation of flowering by up-regulating GI (GIGANTEA)
CC and RCN1 and regulate starch accumulation by down-regulating the alpha-
CC amylase AMY3D. {ECO:0000269|PubMed:19417056}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000305};
CC -!- COFACTOR:
CC Name=Cu cation; Xref=ChEBI:CHEBI:23378;
CC Evidence={ECO:0000250|UniProtKB:P49333};
CC Note=Binds 1 copper ion per dimer. {ECO:0000250|UniProtKB:P49333};
CC -!- SUBUNIT: Homodimer. {ECO:0000250|UniProtKB:P49333}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000250|UniProtKB:P49333}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q0DKM0-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q0DKM0-2; Sequence=VSP_057846;
CC -!- DISRUPTION PHENOTYPE: Chlorina phenotype (PubMed:16891544). Enhanced
CC ethylene sensitivity (PubMed:19417056). {ECO:0000269|PubMed:16891544,
CC ECO:0000269|PubMed:19417056}.
CC -!- SIMILARITY: Belongs to the ethylene receptor family. {ECO:0000305}.
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DR EMBL; AC087551; AAV32219.1; -; Genomic_DNA.
DR EMBL; AP008211; BAF16603.1; -; Genomic_DNA.
DR EMBL; AP014961; BAS92353.1; -; Genomic_DNA.
DR EMBL; CM000142; EEE62384.1; -; Genomic_DNA.
DR EMBL; AK111696; BAG99370.1; -; mRNA.
DR RefSeq; XP_015639200.1; XM_015783714.1. [Q0DKM0-1]
DR AlphaFoldDB; Q0DKM0; -.
DR SMR; Q0DKM0; -.
DR STRING; 4530.OS05T0155200-01; -.
DR PaxDb; Q0DKM0; -.
DR PRIDE; Q0DKM0; -.
DR EnsemblPlants; Os05t0155200-01; Os05t0155200-01; Os05g0155200. [Q0DKM0-2]
DR GeneID; 4337850; -.
DR Gramene; Os05t0155200-01; Os05t0155200-01; Os05g0155200. [Q0DKM0-2]
DR KEGG; osa:4337850; -.
DR eggNOG; KOG0519; Eukaryota.
DR InParanoid; Q0DKM0; -.
DR OrthoDB; 199912at2759; -.
DR PlantReactome; R-OSA-5225756; Ethylene mediated signaling.
DR Proteomes; UP000000763; Chromosome 5.
DR Proteomes; UP000007752; Chromosome 5.
DR Proteomes; UP000059680; Chromosome 5.
DR Genevisible; Q0DKM0; OS.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0051740; F:ethylene binding; IBA:GO_Central.
DR GO; GO:0038199; F:ethylene receptor activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; -; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF47384; SSF47384; 1.
DR SUPFAM; SSF55874; SSF55874; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; ATP-binding; Copper; Disulfide bond;
KW Endoplasmic reticulum; Ethylene signaling pathway; Kinase; Membrane;
KW Metal-binding; Nucleotide-binding; Phosphoprotein; Receptor;
KW Reference proteome; Transferase; Transmembrane; Transmembrane helix;
KW Two-component regulatory system.
FT CHAIN 1..635
FT /note="Probable ethylene response sensor 2"
FT /id="PRO_0000433863"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 159..308
FT /note="GAF"
FT /evidence="ECO:0000305"
FT DOMAIN 351..589
FT /note="Histidine kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT BINDING 66
FT /ligand="Cu cation"
FT /ligand_id="ChEBI:CHEBI:23378"
FT /evidence="ECO:0000250|UniProtKB:P49333"
FT BINDING 70
FT /ligand="Cu cation"
FT /ligand_id="ChEBI:CHEBI:23378"
FT /evidence="ECO:0000250|UniProtKB:P49333"
FT MOD_RES 354
FT /note="Phosphohistidine; by autocatalysis"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT DISULFID 5
FT /note="Interchain"
FT /evidence="ECO:0000250|UniProtKB:P49333"
FT DISULFID 7
FT /note="Interchain"
FT /evidence="ECO:0000250|UniProtKB:P49333"
FT VAR_SEQ 517..635
FT /note="KDTGCGISPQDMPHTFRKFAHPENAGKWNSGSGLGLALSRRFVSLMEGNIWL
FT ESEGVGKGCTAMFFVKLGMPEKPNANLRRMAPHPLQPNQGAGGPDALSISIMDSNPRVP
FT RVRYQSSV -> CS (in isoform 2)"
FT /id="VSP_057846"
SQ SEQUENCE 635 AA; 70518 MW; 2C5769466EF28149 CRC64;
MDGSCDCIEP LWQADDLLVK YQYISDFFIA LAYFSIPLEL IYFVKKSAFF PYRWVLIQFG
AFIVLCGATH LINLWTFAIY TKTIAVVLTV AKAATAVVSC ITALMLVHII PDLLNVKLRE
RFLKDKADEL DREMGIIRTQ EETGRHVHML THEIRSTLDR HTILRTTLVE LGRTLVLAEC
ALWMPTRSGS ALQLSHTIYN SAAIGSVVPI NLPIVSKVFN SNRVVKIPHT SPLASITADK
SRYVPPEVVA IRVPLLHLTN FQINDWPELS AKSFAVMVLM LPPDSAREWR PHERELVEVV
ADQVAVALSH AAILEESMRA RDLLMEQNIA LDAARREAEM AICARNDFLA VMNHEMRTPM
RAIVSLSSLL LETNLSAEQR LMVETILKSS DLLATLTNDV LDVSKLENGS LELEIAPFNL
HSTFTDVVNL IKPVAACKRL SVMVTLAPEL PLHAIGDQKR LMQIILNVAG NSIKFTKEGH
VSITASMARP DALRGPHEPD YHPVVSDGFF YLAVQVKDTG CGISPQDMPH TFRKFAHPEN
AGKWNSGSGL GLALSRRFVS LMEGNIWLES EGVGKGCTAM FFVKLGMPEK PNANLRRMAP
HPLQPNQGAG GPDALSISIM DSNPRVPRVR YQSSV
