ID   ERT1_POSPM              Reviewed;         393 AA.
AC   B8PBQ6;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Transcription activator of gluconeogenesis ERT1;
GN   Name=ERT1; ORFNames=POSPLDRAFT_113058;
OS   Postia placenta (strain ATCC 44394 / Madison 698-R) (Brown rot fungus)
OS   (Poria monticola).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Dacryobolaceae; Postia.
OX   NCBI_TaxID=561896;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 44394 / Madison 698-R;
RX   PubMed=19193860; DOI=10.1073/pnas.0809575106;
RA   Martinez D., Challacombe J., Morgenstern I., Hibbett D., Schmoll M.,
RA   Kubicek C.P., Ferreira P., Ruiz-Duenas F.J., Martinez A.T., Kersten P.,
RA   Hammel K.E., Vanden Wymelenberg A., Gaskell J., Lindquist E., Sabat G.,
RA   Splinter BonDurant S., Larrondo L.F., Canessa P., Vicuna R., Yadav J.,
RA   Doddapaneni H., Subramanian V., Pisabarro A.G., Lavin J.L., Oguiza J.A.,
RA   Master E., Henrissat B., Coutinho P.M., Harris P., Magnuson J.K.,
RA   Baker S.E., Bruno K., Kenealy W., Hoegger P.J., Kuees U., Ramaiya P.,
RA   Lucas S., Salamov A., Shapiro H., Tu H., Chee C.L., Misra M., Xie G.,
RA   Teter S., Yaver D., James T., Mokrejs M., Pospisek M., Grigoriev I.V.,
RA   Brettin T., Rokhsar D., Berka R., Cullen D.;
RT   "Genome, transcriptome, and secretome analysis of wood decay fungus Postia
RT   placenta supports unique mechanisms of lignocellulose conversion.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:1954-1959(2009).
CC   -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC       utilization. Activator of gluconeogenetic genes (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
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DR   EMBL; EQ966304; EED81673.1; -; Genomic_DNA.
DR   RefSeq; XP_002473103.1; XM_002473058.1.
DR   AlphaFoldDB; B8PBQ6; -.
DR   STRING; 561896.B8PBQ6; -.
DR   EnsemblFungi; EED81673; EED81673; POSPLDRAFT_113058.
DR   KEGG; ppl:POSPLDRAFT_113058; -.
DR   HOGENOM; CLU_010748_2_1_1; -.
DR   InParanoid; B8PBQ6; -.
DR   OMA; SECKETI; -.
DR   Proteomes; UP000001743; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR   CDD; cd00067; GAL4; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF55785; SSF55785; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS50112; PAS; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Gluconeogenesis; Metal-binding; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation; Zinc.
FT   CHAIN           1..393
FT                   /note="Transcription activator of gluconeogenesis ERT1"
FT                   /id="PRO_0000406468"
FT   DOMAIN          275..348
FT                   /note="PAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT   DNA_BIND        73..101
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          1..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          161..198
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..27
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        28..47
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        161..185
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   393 AA;  43233 MW;  0A91F5511DE3A4C3 CRC64;
     MSSALTQQPA YRLAPSASSS TSDINAAPDA DSKKKTGTKR RRPQDGTSDS ADSSSQPPRT
     REGPKKKKAN RACFHCQKAH LTCDDSRPCQ RCVKRGMADN CTEGHRKKAK YLLDEEELAQ
     PDPPYVPPDP MFPSSYTASA PFSLGSEGAN LEYSILSAIL GNSPDPTGPP NSGSPSVSHA
     PQPSAPFNGQ PDIGAGSAIS GGAQGAAAVY QAVTKPYDYT EGYHFLMKHL PTRFDKNDIL
     RIVRALAIFR PSLIALQMPL SEEDEVFVEK CFQRSLIELD KLVSFSGTPT VAWRRTGEIC
     LVGPEFCMLT GWEKEELVGR RKYIYELFEN QSVVEYWENF ANHAFENTTQ SVYSHCVLLK
     PSGTPVPCTF CFSIRRDIMD LPSLVIGQWL PLL