ERT1_USTMA
ID ERT1_USTMA Reviewed; 721 AA.
AC Q4PD88; A0A0D1CC49;
DT 05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT 16-SEP-2015, sequence version 2.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Transcription activator of gluconeogenesis ERT1;
GN Name=ERT1; ORFNames=UMAG_10450;
OS Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX NCBI_TaxID=237631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=521 / FGSC 9021;
RX PubMed=17080091; DOI=10.1038/nature05248;
RA Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA Birren B.W.;
RT "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT maydis.";
RL Nature 444:97-101(2006).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=521 / FGSC 9021;
RA Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC utilization. Activator of gluconeogenetic genes (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
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DR EMBL; CM003142; KIS70772.1; -; Genomic_DNA.
DR RefSeq; XP_011387974.1; XM_011389672.1.
DR AlphaFoldDB; Q4PD88; -.
DR SMR; Q4PD88; -.
DR PRIDE; Q4PD88; -.
DR EnsemblFungi; KIS70772; KIS70772; UMAG_10450.
DR GeneID; 23566486; -.
DR KEGG; uma:UMAG_10450; -.
DR VEuPathDB; FungiDB:UMAG_10450; -.
DR eggNOG; ENOG502R1M5; Eukaryota.
DR HOGENOM; CLU_010748_2_0_1; -.
DR InParanoid; Q4PD88; -.
DR OrthoDB; 681770at2759; -.
DR Proteomes; UP000000561; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009267; P:cellular response to starvation; IBA:GO_Central.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR CDD; cd00067; GAL4; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 4.10.240.10; -; 1.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR SMART; SM00066; GAL4; 1.
DR SUPFAM; SSF55785; SSF55785; 1.
DR SUPFAM; SSF57701; SSF57701; 1.
DR PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE 3: Inferred from homology;
KW Activator; DNA-binding; Gluconeogenesis; Metal-binding; Nucleus;
KW Reference proteome; Transcription; Transcription regulation; Zinc.
FT CHAIN 1..721
FT /note="Transcription activator of gluconeogenesis ERT1"
FT /id="PRO_0000406470"
FT DOMAIN 606..673
FT /note="PAS"
FT DNA_BIND 174..202
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT REGION 1..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 196..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..233
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..294
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 721 AA; 76603 MW; 8CC0294091172B24 CRC64;
MSSAKGDKLA PRPPSYGSNQ SATPTYSLPP HPSTTYPQRH QSPASHAAAS TLAALASSPP
ASSSTASPHP PNVLPTPSSA STSYNARPST TSTLNQSLYS SSASPAAKAA TAGISPSGSP
LRKEVHMSST KQTPAASTST LAKPASSSTT GTPTPSSASK ESGSSKRKKA TRACLHCQKA
HLTCDDSRPC QRCVKKGLAE SCMDGRRKKA KYLLDDDELE ELRRQKEAKK AAKQAVQQKN
APSPQQRQSR PSQQDSAKST PQNSDPSSEK ASAVSSILDQ VAGSIATPSS SGHGPSPHAH
DYLSSNPFDS SNGGVDDTQA SSNNGGALPF DLSFDPSTHN FGSEATSLEY SILSSMLNGT
DLQLMGASGA SPDLQASPAV GVMNGWNIAS GELDAILNIS MQQNQVPGAG GMDTVAATYS
DTADMGVYAD PQPNTGLQDV GGGDSALNAL EVPSSQCTAK EEPILLSSGS GNGNGNGSGS
GSGEAQQAGS NNQVDLGSSS QRSTSNEPVA ADINRAIASR RVARQQQDTI WRARIAKTYR
DNTAPFPYPE GYHFLIKYVT SKYEKQDVLR IVRALAIFRP SLIALQMPLT EEDEIFVERS
FQRTMLEFEK LISFSGTPTV VWRRTCEICV VGAEFCMLTQ WSKDQLMGRR IYEFMDKNST
LDYWENFAQH AFENTTQSVM TTCTLVKPDG KLVPCAWSFT IKRDIFDLPS LVVGNFLPIL
S
