ID   ERTS_RAT                Reviewed;          68 AA.
AC   P68313; P00972;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Erythrodihydroneopterin triphosphate synthetase;
DE            EC=6.-.-.-;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   PROTEIN SEQUENCE, AND VARIANT ASP-8 INS.
RC   TISSUE=Brain, and Liver;
RA   Gal E.M., Sherman A.D.;
RT   "6-(D-erythro-1',2',3'-trihydroxypropyl)-7,8-dihydropterin triphosphate
RT   synthetase.";
RL   Fed. Proc. 38:324-324(1979).
RN   [2]
RP   PHOSPHORYLATION AT SER-66.
RX   PubMed=697844; DOI=10.1016/0006-291x(78)91031-8;
RA   Gal E.M., Sherman A.D.;
RT   "Phosphorylation, a factor controlling the synthesis of L-
RT   erythrodihydrobiopterin (BH2).";
RL   Biochem. Biophys. Res. Commun. 83:593-598(1978).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; A01203; SYRTPP.
DR   AlphaFoldDB; P68313; -.
DR   iPTMnet; P68313; -.
DR   PhosphoSitePlus; P68313; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Ligase; Phosphoprotein; Reference proteome.
FT   CHAIN           1..68
FT                   /note="Erythrodihydroneopterin triphosphate synthetase"
FT                   /id="PRO_0000087035"
FT   MOD_RES         66
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:697844"
FT   VARIANT         8
FT                   /note="D -> DD (in brain)"
FT                   /evidence="ECO:0000269|Ref.1"
SQ   SEQUENCE   68 AA;  7837 MW;  EA821E4E1C40049F CRC64;
     ISHGFRYDAI AKLFRPFFCG DGYGHRIGET VYYAGSLKYC ARSFDVGAEI ICKGFYYFGI
     YKRRVSEV