ESAB_STAAS
ID ESAB_STAAS Reviewed; 80 AA.
AC Q6GCI7;
DT 05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=Type VII secretion system accessory factor EsaB {ECO:0000250|UniProtKB:P0C050};
GN Name=esaB {ECO:0000250|UniProtKB:P0C050}; OrderedLocusNames=SAS0261;
OS Staphylococcus aureus (strain MSSA476).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=282459;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSSA476;
RX PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT for the rapid evolution of virulence and drug resistance.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC -!- FUNCTION: Seems to regulate secreted factors that contribute to the
CC establishment of persistent infections in the host.
CC {ECO:0000250|UniProtKB:P0C050}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P0C050}.
CC -!- SIMILARITY: Belongs to the EsaB family. {ECO:0000305}.
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DR EMBL; BX571857; CAG42032.1; -; Genomic_DNA.
DR RefSeq; WP_001071606.1; NC_002953.3.
DR AlphaFoldDB; Q6GCI7; -.
DR SMR; Q6GCI7; -.
DR GeneID; 66838588; -.
DR KEGG; sas:SAS0261; -.
DR HOGENOM; CLU_189011_2_0_9; -.
DR OMA; MAKDTHM; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR014921; EsaB.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR024962; YukD-like.
DR Pfam; PF08817; YukD; 1.
DR PIRSF; PIRSF037793; DUF_ubiquitin-like_YukD; 1.
DR SUPFAM; SSF54236; SSF54236; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Virulence.
FT CHAIN 1..80
FT /note="Type VII secretion system accessory factor EsaB"
FT /id="PRO_0000087047"
SQ SEQUENCE 80 AA; 9121 MW; 28C666A3B6F99FA6 CRC64;
MNQHVKVTFD FTNYNYGTYD LAVPAYLPIK NLIALVLDSL DISIFDVNTQ IKVMTKGQLL
VENDRLIDYQ IADGDILKLL