ID   ESAR_PANSE              Reviewed;         249 AA.
AC   P54293;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Transcriptional activator protein EsaR;
GN   Name=esaR;
OS   Pantoea stewartii subsp. stewartii (Erwinia stewartii).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Pantoea.
OX   NCBI_TaxID=66271;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=SS104;
RX   PubMed=7665477; DOI=10.1128/jb.177.17.5000-5008.1995;
RA   von Bodman S.B., Farrand S.K.;
RT   "Capsular polysaccharide biosynthesis and pathogenicity in Erwinia
RT   stewartii require induction by an N-acylhomoserine lactone autoinducer.";
RL   J. Bacteriol. 177:5000-5008(1995).
CC   -!- FUNCTION: Functions as a potential OhlL-responsive transcriptional
CC       regulator.
CC   -!- INTERACTION:
CC       P54293; P54293: esaR; NbExp=2; IntAct=EBI-6416680, EBI-6416680;
CC   -!- SIMILARITY: Belongs to the autoinducer-regulated transcriptional
CC       regulatory protein family. {ECO:0000305}.
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DR   EMBL; L32184; AAA82097.1; -; Genomic_DNA.
DR   RefSeq; WP_006119203.1; NZ_VZPF01000009.1.
DR   AlphaFoldDB; P54293; -.
DR   SMR; P54293; -.
DR   PRIDE; P54293; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.450.80; -; 1.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR005143; TF_LuxR_autoind-bd_dom.
DR   InterPro; IPR036693; TF_LuxR_autoind-bd_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF03472; Autoind_bind; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF75516; SSF75516; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   1: Evidence at protein level;
KW   Activator; DNA-binding; Quorum sensing; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..249
FT                   /note="Transcriptional activator protein EsaR"
FT                   /id="PRO_0000184151"
FT   DOMAIN          174..239
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        198..217
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
SQ   SEQUENCE   249 AA;  28103 MW;  77733728FE78298A CRC64;
     MFSFFLENQT ITDTLQTYIQ RKLSPLGSPD YAYTVVSKKN PSNVLIISSY PDEWIRLYRA
     NNFQLTDPVI LTAFKRTSPF AWDENITLMS DLRFTKIFSL SKQYNIVNGF TYVLHDHMNN
     LALLSVIIKG NDQTALEQRL AAEQGTMQML LIDFNEQMYR LAGTEGERAP ALNQSADKTI
     FSSRENEVLY WASMGKTYAE IAAITGISVS TVKFHIKNVV VKLGVSNARQ AIRLGVELDL
     IRPAASAAR