ID   ESF11_ARATH             Reviewed;          83 AA.
AC   A8MSA6;
DT   03-SEP-2014, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=EMBRYO SURROUNDING FACTOR 1.1;
DE   AltName: Full=Maternally expressed family protein 1.1;
DE   AltName: Full=Maternally expressed gene 1.1;
DE   Flags: Precursor;
GN   Name=ESF1.1; Synonyms=MEG1.1; OrderedLocusNames=At1g10747;
GN   ORFNames=F20B24, T16B5;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND DISRUPTION
RP   PHENOTYPE.
RX   PubMed=24723605; DOI=10.1126/science.1243005;
RA   Costa L.M., Marshall E., Tesfaye M., Silverstein K.A., Mori M., Umetsu Y.,
RA   Otterbach S.L., Papareddy R., Dickinson H.G., Boutiller K.,
RA   VandenBosch K.A., Ohki S., Gutierrez-Marcos J.F.;
RT   "Central cell-derived peptides regulate early embryo patterning in
RT   flowering plants.";
RL   Science 344:168-172(2014).
CC   -!- FUNCTION: Maternally-contributed central cell peptide regulating
CC       suspensor development and correct auxin distribution in early
CC       developing embryos. {ECO:0000269|PubMed:24723605}.
CC   -!- TISSUE SPECIFICITY: Expressed exclusively in ovule embryo sacs and in
CC       early developing endosperms. {ECO:0000269|PubMed:24723605}.
CC   -!- DEVELOPMENTAL STAGE: Primarily expressed in the central cell gamete of
CC       nonfrtilized ovules, which upon fertilization gives rise to the
CC       endosperm, and later in the micropylar endosperm, which surrounds the
CC       embryo. {ECO:0000269|PubMed:24723605}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype, due to redundancy with
CC       ESF1.2 and ESF1.3. Simultaneous down-regulation of all 3 genes by RNAi
CC       induces embryo abnormalities. {ECO:0000269|PubMed:24723605}.
CC   -!- SIMILARITY: Belongs to the MEG family. {ECO:0000305}.
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DR   EMBL; AC007354; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC009398; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002684; AEE28641.1; -; Genomic_DNA.
DR   RefSeq; NP_001077511.1; NM_001084042.2.
DR   AlphaFoldDB; A8MSA6; -.
DR   SMR; A8MSA6; -.
DR   STRING; 3702.AT1G10747.1; -.
DR   PaxDb; A8MSA6; -.
DR   PRIDE; A8MSA6; -.
DR   EnsemblPlants; AT1G10747.1; AT1G10747.1; AT1G10747.
DR   GeneID; 5007680; -.
DR   Gramene; AT1G10747.1; AT1G10747.1; AT1G10747.
DR   KEGG; ath:AT1G10747; -.
DR   Araport; AT1G10747; -.
DR   TAIR; locus:4010713429; AT1G10747.
DR   HOGENOM; CLU_183999_1_0_1; -.
DR   OMA; WHDREIC; -.
DR   OrthoDB; 1615625at2759; -.
DR   PhylomeDB; A8MSA6; -.
DR   PRO; PR:A8MSA6; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   GO; GO:0000578; P:embryonic axis specification; IMP:UniProtKB.
DR   GO; GO:0010098; P:suspensor development; IMP:UniProtKB.
DR   InterPro; IPR041608; ESF1_brassicaceae.
DR   Pfam; PF18209; ESF1; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Disulfide bond; Reference proteome; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..83
FT                   /note="EMBRYO SURROUNDING FACTOR 1.1"
FT                   /id="PRO_0000430059"
FT   DISULFID        41..56
FT                   /evidence="ECO:0000250"
FT   DISULFID        46..75
FT                   /evidence="ECO:0000250"
FT   DISULFID        54..71
FT                   /evidence="ECO:0000250"
FT   DISULFID        57..64
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   83 AA;  9551 MW;  853660839FD35E6D CRC64;
     MKSSHTSLIC ILMLSLVALH QCVRMKVKEI GRSNKIYIPP CFRDSCDHVL KKDCYCCGSK
     PDLCWEDQHY CNTHCPPLKP LIN