ESF2_CHAGB
ID ESF2_CHAGB Reviewed; 332 AA.
AC Q2GZQ4;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2007, sequence version 2.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Pre-rRNA-processing protein ESF2;
DE AltName: Full=18S rRNA factor 2;
GN Name=ESF2; ORFNames=CHGG_04992;
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970;
RX PubMed=25720678; DOI=10.1128/genomea.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC -!- FUNCTION: Involved in the small subunit (SSU) processome assembly and
CC function, and in the 18S rRNA synthesis. Required for the early
CC cleavages at sites A0, A1 and A2 (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ESF2/ABP1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAQ88373.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EAQ88373.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; CH408032; EAQ88373.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_001224206.1; XM_001224205.1.
DR AlphaFoldDB; Q2GZQ4; -.
DR STRING; 38033.XP_001224206.1; -.
DR EnsemblFungi; EAQ88373; EAQ88373; CHGG_04992.
DR GeneID; 4392017; -.
DR eggNOG; KOG3152; Eukaryota.
DR HOGENOM; CLU_054086_0_1_1; -.
DR InParanoid; Q2GZQ4; -.
DR OrthoDB; 1377351at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR CDD; cd12263; RRM_ABT1_like; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR039119; ABT1/Esf2.
DR InterPro; IPR034353; ABT1/ESF2_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR12311; PTHR12311; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribosome biogenesis; RNA-binding;
KW rRNA processing.
FT CHAIN 1..332
FT /note="Pre-rRNA-processing protein ESF2"
FT /id="PRO_0000285368"
FT DOMAIN 121..211
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 1..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 269..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..45
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..96
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..286
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 332 AA; 37197 MW; 57D01E7537799CD4 CRC64;
MSTDKRNQFL DAGDSEDDAG HGYDSEEDLQ KGGRSAKRRR VDDDDSDAED VSDQEEEHGE
DGATNLREGT ADSEAARDDE EIAEEGPKDD KADLPAELPG VSKPLAKKNL VASEAAIKKS
GVVYLSRIPP FMKPAKLRSL LEPYGKINRI FLTPEDPTEH TRRVRNGGNK KRSFTEGWVE
FVKKKDAKKV CDLLNAQTIG GKKSSWYHDD VWALKYLNGF KWHHLTEQIS AENAERTSRI
RAEVAKTTRE NKEFVRNVER AKVINGIQSK AAAKRKKTDD SEEAAGSGEA VGKTEGESAQ
DKRRTFKQIL LAKKRKHEEQ PAHVLRVLSK IF
