ID   ESFL4_ARATH             Reviewed;          74 AA.
AC   Q1G3R6; A0MDP9;
DT   03-SEP-2014, integrated into UniProtKB/Swiss-Prot.
DT   27-JUN-2006, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=EMBRYO SURROUNDING FACTOR 1-like protein 4;
DE   Flags: Precursor;
GN   Name=ESFL4; OrderedLocusNames=At2g41415; ORFNames=F13H10;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Silverstein K.A.T., Moskal W.A., Wu H.C., Underwood B.A., Graham M.A.,
RA   Town C.D., VandenBosch K.A.;
RT   "Small cysteine-rich peptides resembling antimicrobial peptides have been
RT   under-predicted in plants.";
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [5]
RP   IDENTIFICATION, AND TISSUE SPECIFICITY.
RX   PubMed=24723605; DOI=10.1126/science.1243005;
RA   Costa L.M., Marshall E., Tesfaye M., Silverstein K.A., Mori M., Umetsu Y.,
RA   Otterbach S.L., Papareddy R., Dickinson H.G., Boutiller K.,
RA   VandenBosch K.A., Ohki S., Gutierrez-Marcos J.F.;
RT   "Central cell-derived peptides regulate early embryo patterning in
RT   flowering plants.";
RL   Science 344:168-172(2014).
CC   -!- TISSUE SPECIFICITY: expressed in flowers.
CC       {ECO:0000269|PubMed:24723605}.
CC   -!- SIMILARITY: Belongs to the MEG family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK28332.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DQ487518; ABF59215.1; -; mRNA.
DR   EMBL; AC005662; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002685; AEC09971.1; -; Genomic_DNA.
DR   EMBL; DQ652665; ABK28332.1; ALT_SEQ; mRNA.
DR   RefSeq; NP_001078036.1; NM_001084567.2.
DR   AlphaFoldDB; Q1G3R6; -.
DR   STRING; 3702.AT2G41415.1; -.
DR   PaxDb; Q1G3R6; -.
DR   PRIDE; Q1G3R6; -.
DR   ProteomicsDB; 220584; -.
DR   EnsemblPlants; AT2G41415.1; AT2G41415.1; AT2G41415.
DR   GeneID; 5007952; -.
DR   Gramene; AT2G41415.1; AT2G41415.1; AT2G41415.
DR   KEGG; ath:AT2G41415; -.
DR   Araport; AT2G41415; -.
DR   TAIR; locus:4010713698; AT2G41415.
DR   HOGENOM; CLU_183999_1_0_1; -.
DR   OMA; KIDMSVC; -.
DR   OrthoDB; 1633324at2759; -.
DR   PhylomeDB; Q1G3R6; -.
DR   PRO; PR:Q1G3R6; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q1G3R6; baseline and differential.
DR   GO; GO:0010098; P:suspensor development; IEA:InterPro.
DR   InterPro; IPR041608; ESF1_brassicaceae.
DR   Pfam; PF18209; ESF1; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Reference proteome; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..74
FT                   /note="EMBRYO SURROUNDING FACTOR 1-like protein 4"
FT                   /id="PRO_0000430065"
FT   DISULFID        36..51
FT                   /evidence="ECO:0000250"
FT   DISULFID        41..70
FT                   /evidence="ECO:0000250"
FT   DISULFID        49..66
FT                   /evidence="ECO:0000250"
FT   DISULFID        52..59
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   74 AA;  8271 MW;  0E1453DF96538E40 CRC64;
     MKSSHAYLVC ILLLSLFSLH QCVRLERSNK IDMSVCVHEI CGGVFDGGCY CCPKTPALCW
     ADIQFCTTYC QSQT