ID   ESG1_TRYBB              Reviewed;         325 AA.
AC   P04477;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   13-AUG-1987, sequence version 1.
DT   03-AUG-2022, entry version 44.
DE   RecName: Full=VSG expression site-associated protein 117A;
DE   AltName: Full=ESAG protein;
DE   Flags: Precursor;
OS   Trypanosoma brucei brucei.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=5702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2861910; DOI=10.1016/s0092-8674(85)80113-6;
RA   Cully D.F., Ip H.S., Cross G.A.M.;
RT   "Coordinate transcription of variant surface glycoprotein genes and an
RT   expression site associated gene family in Trypanosoma brucei.";
RL   Cell 42:173-182(1985).
CC   -!- FUNCTION: Not known but may be related to activation of the variant
CC       surface glycoprotein genes.
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DR   EMBL; M11451; AAA30190.1; -; mRNA.
DR   PIR; A03394; VMUT17.
DR   AlphaFoldDB; P04477; -.
DR   PRIDE; P04477; -.
DR   InterPro; IPR004922; ESAG.
DR   Pfam; PF03238; ESAG1; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Signal.
FT   SIGNAL          1..23
FT   CHAIN           24..325
FT                   /note="VSG expression site-associated protein 117A"
FT                   /id="PRO_0000021204"
FT   CARBOHYD        72
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        290
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        313
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   325 AA;  35993 MW;  A6DF1BA0EEC43379 CRC64;
     MKVTIVELVV WLFSVNFFVV VAEESRWTLV DDHYGKNLHE SVCYLRCLSN ALNKLYSEGE
     RRLFVNEEVY ANASRILDDM EGKTGESTTY LSVVSSEMGG ENNKLEKLIS YGNAMGDLVA
     KVGGLFAEVN ESVRAVREEI PSALIRANKY YTAIAEITRT VWDDVNRPLQ QDKATCGDQK
     VTGVGELKTE CGAHTCPLSD GVNESALQKY KGGCLEINVM SGSVSECFNL PRNKLYRSVA
     LSSSHGFLKW YQDEAKRFQL GLRVKNIFGP LIASFGVGQP PSVLAEMINN ITSLQSRFNE
     VHSNFTSILL ADNLTADVDN TDSTI