ID   ESL1_MYCGE              Reviewed;         268 AA.
AC   Q49412;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Putative esterase/lipase 1;
DE            EC=3.1.-.-;
GN   OrderedLocusNames=MG310;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
CC   -!- SIMILARITY: Belongs to the lipase/esterase LIP3/BchO family.
CC       {ECO:0000305}.
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DR   EMBL; L43967; AAC71532.1; -; Genomic_DNA.
DR   PIR; C64234; C64234.
DR   RefSeq; WP_009885888.1; NZ_AAGX01000008.1.
DR   AlphaFoldDB; Q49412; -.
DR   STRING; 243273.MG_310; -.
DR   ESTHER; mycge-esl1; AlphaBeta_hydrolase.
DR   EnsemblBacteria; AAC71532; AAC71532; MG_310.
DR   KEGG; mge:MG_310; -.
DR   eggNOG; COG2267; Bacteria.
DR   HOGENOM; CLU_020336_41_1_14; -.
DR   OMA; FRTHFKD; -.
DR   OrthoDB; 1119700at2; -.
DR   BioCyc; MGEN243273:G1GJ2-379-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016298; F:lipase activity; IBA:GO_Central.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR022742; Hydrolase_4.
DR   Pfam; PF12146; Hydrolase_4; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome; Serine esterase.
FT   CHAIN           1..268
FT                   /note="Putative esterase/lipase 1"
FT                   /id="PRO_0000207074"
FT   ACT_SITE        27
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        94
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   268 AA;  30747 MW;  7300775DAD753376 CRC64;
     MRLEIENGLE FVNDPVVNEL GKICFFHPFT GNLTNKLSFR SHFNRYSFYA INYPGHGNSV
     INNPKQLEFS YWLEITKQFF DKHNLKDVIL FGHSIGGGLA VALTNYLSSD QYKAVLLEAP
     LNPAIVETPL NIVQNLIPDP DSDFAVIQKC LVYNIEKKLG ANFKEYCERE KQKSIHQNQR
     LKVMLEPSTL KQNIVLINAA FLKLNCPALW IHGKQDGIIK YLPSKAYYES LNNKQIQFKA
     IEAAAHTPYF EQPQKFLSLV NDFFQLIS