ID   ESL3_MYCGE              Reviewed;         273 AA.
AC   Q49421; Q49335;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Putative esterase/lipase 3;
DE            EC=3.1.-.-;
GN   OrderedLocusNames=MG344;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 193-255.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA   Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT   "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL   J. Bacteriol. 175:7918-7930(1993).
CC   -!- SIMILARITY: Belongs to the lipase/esterase LIP3/BchO family.
CC       {ECO:0000305}.
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DR   EMBL; L43967; AAC71569.1; -; Genomic_DNA.
DR   EMBL; U02222; AAA03376.1; -; Genomic_DNA.
DR   PIR; A64238; A64238.
DR   RefSeq; WP_009885800.1; NZ_AAGX01000006.1.
DR   AlphaFoldDB; Q49421; -.
DR   SMR; Q49421; -.
DR   STRING; 243273.MG_344; -.
DR   ESTHER; mycge-esl3; AlphaBeta_hydrolase.
DR   EnsemblBacteria; AAC71569; AAC71569; MG_344.
DR   KEGG; mge:MG_344; -.
DR   eggNOG; COG2267; Bacteria.
DR   HOGENOM; CLU_020336_41_1_14; -.
DR   OMA; TSNESWM; -.
DR   OrthoDB; 1119700at2; -.
DR   BioCyc; MGEN243273:G1GJ2-431-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   Pfam; PF12697; Abhydrolase_6; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome; Serine esterase.
FT   CHAIN           1..273
FT                   /note="Putative esterase/lipase 3"
FT                   /id="PRO_0000207078"
FT   ACT_SITE        34
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        100
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   273 AA;  31836 MW;  C68C43B733F1F56C CRC64;
     MKRFSDLNQI DISKLEVFFQ PAKKTKKQTV VFAHGFSVFH SYFQSFYKTL TDYDYYAPLW
     PGHNVNGFDY KELSPIHYGE LLAAFIENKD LENIVLIGHS MGAAVCSYAM NLLNAKRVEK
     LILLAPLSYC NLLRYFKIKS SFKKDKAERM ANFKAMFQTK FSNLTDENSW ENELSKHSKM
     AKKLSNNILK ELPVLNKTYK NLKLPVFLVL AQNDLFMPTK LTLSYFNKYL IKNNNLQSSV
     ILNSEHQMFN SKYESFCKAM DDILNHNKLS KIY