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ESPG3_MYCTO
ID   ESPG3_MYCTO             Reviewed;         295 AA.
AC   P9WJC6; L0T4X8; O53694; Q7DA33;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=ESX-3 secretion-associated protein EspG3 {ECO:0000305};
GN   Name=espG3 {ECO:0000250|UniProtKB:P9WJC7}; OrderedLocusNames=MT0302;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Specific chaperone for cognate PE/PPE proteins. Plays an
CC       important role in preventing aggregation of PE/PPE dimers.
CC       {ECO:0000250|UniProtKB:O53943}.
CC   -!- SUBUNIT: Interacts specifically with ESX-3-dependent PE/PPE proteins.
CC       {ECO:0000250|UniProtKB:O53943}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:B2HSU5}.
CC   -!- SIMILARITY: Belongs to the EspG family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK44526.1; -; Genomic_DNA.
DR   PIR; G70836; G70836.
DR   RefSeq; WP_003401521.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WJC6; -.
DR   SASBDB; P9WJC6; -.
DR   SMR; P9WJC6; -.
DR   EnsemblBacteria; AAK44526; AAK44526; MT0302.
DR   GeneID; 45424263; -.
DR   KEGG; mtc:MT0302; -.
DR   PATRIC; fig|83331.31.peg.325; -.
DR   HOGENOM; CLU_073321_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR025734; EspG.
DR   Pfam; PF14011; ESX-1_EspG; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm.
FT   CHAIN           1..295
FT                   /note="ESX-3 secretion-associated protein EspG3"
FT                   /id="PRO_0000427853"
SQ   SEQUENCE   295 AA;  31559 MW;  B55062E063E944D7 CRC64;
     MDATPNAVEL TVDNAWFIAE TIGAGTFPWV LAITMPYSDA AQRGAFVDRQ RDELTRMGLL
     SPQGVINPAV ADWIKVVCFP DRWLDLRYVG PASADGACEL LRGIVALRTG TGKTSNKTGN
     GVVALRNAQL VTFTAMDIDD PRALVPILGV GLAHRPPARF DEFSLPTRVG ARADERLRSG
     VPLGEVVDYL GIPASARPVV ESVFSGPRSY VEIVAGCNRD GRHTTTEVGL SIVDTSAGRV
     LVSPSRAFDG EWVSTFSPGT PFAIAVAIQT LTACLPDGQW FPGQRVSRDF STQSS
 
 
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