ID   ESR1_MAIZE              Reviewed;         131 AA.
AC   O24602; Q7DLW1;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=CLAVATA3/ESR (CLE)-related protein ESR1 {ECO:0000303|PubMed:18034320};
DE            Short=ZmESR1 {ECO:0000303|PubMed:18034320};
DE   AltName: Full=Embryo surrounding region protein 1 {ECO:0000303|PubMed:9263463};
DE   Contains:
DE     RecName: Full=ESR1p {ECO:0000303|PubMed:9263463};
DE   Flags: Precursor;
GN   Name=ESR1 {ECO:0000303|PubMed:18034320};
GN   Synonyms=ESR1c1 {ECO:0000303|PubMed:9263463},
GN   ESR1g1 {ECO:0000303|PubMed:9263463}, ESR1g2 {ECO:0000303|PubMed:9263463};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], TISSUE SPECIFICITY, AND
RP   DEVELOPMENTAL STAGE.
RC   STRAIN=cv. A188; TISSUE=Endosperm, and Leaf;
RX   PubMed=9263463; DOI=10.1046/j.1365-313x.1997.12010235.x;
RA   Opsahl-Ferstad H.G., Le Deunff E., Dumas C., Rogowsky P.M.;
RT   "ZmEsr, a novel endosperm-specific gene expressed in a restricted region
RT   around the maize embryo.";
RL   Plant J. 12:235-246(1997).
RN   [2]
RP   TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND SUBCELLULAR LOCATION.
RX   PubMed=12096094; DOI=10.1093/jxb/erf010;
RA   Bonello J.-F., Sevilla-Lecoq S., Berne A., Risueno M.-C., Dumas C.,
RA   Rogowsky P.M.;
RT   "Esr proteins are secreted by the cells of the embryo surrounding region.";
RL   J. Exp. Bot. 53:1559-1568(2002).
RN   [3]
RP   REVIEW.
RX   PubMed=18034320; DOI=10.1007/s00018-007-7411-5;
RA   Jun J.H., Fiume E., Fletcher J.C.;
RT   "The CLE family of plant polypeptide signaling molecules.";
RL   Cell. Mol. Life Sci. 65:743-755(2008).
RN   [4]
RP   REVIEW.
RX   PubMed=20016993; DOI=10.1007/s00709-009-0095-y;
RA   Wang G., Fiers M.;
RT   "CLE peptide signaling during plant development.";
RL   Protoplasma 240:33-43(2010).
CC   -!- FUNCTION: [ESR1p]: Extracellular signal peptide that regulates cell
CC       fate. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: [ESR1p]: Secreted, extracellular space
CC       {ECO:0000269|PubMed:12096094}.
CC   -!- TISSUE SPECIFICITY: [ESR1p]: Seed endosperm.
CC       {ECO:0000269|PubMed:12096094, ECO:0000269|PubMed:9263463}.
CC   -!- DEVELOPMENTAL STAGE: [ESR1p]: Expressed specifically in the embryo
CC       surrounding region at the micropylar end of the seed endosperm at early
CC       stages (4 to 7 days after pollination, DAP) and ever-decreasing parts
CC       of the suspensor at subsequent stages (at protein level).
CC       {ECO:0000269|PubMed:12096094, ECO:0000269|PubMed:9263463}.
CC   -!- PTM: [ESR1p]: The O-glycosylation (arabinosylation) of the
CC       hydroxyproline Pro-84 enhances binding affinity of the ESR1p peptide
CC       for its receptor. {ECO:0000250|UniProtKB:O49519}.
CC   -!- SIMILARITY: Belongs to the CLV3/ESR signal peptide family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X98496; CAA67122.1; -; mRNA.
DR   EMBL; X98497; CAA67123.1; -; Genomic_DNA.
DR   EMBL; X99968; CAA68230.1; -; Genomic_DNA.
DR   PIR; T03279; T03279.
DR   RefSeq; NP_001105956.1; NM_001112486.2.
DR   AlphaFoldDB; O24602; -.
DR   STRING; 4577.GRMZM2G046086_P01; -.
DR   PaxDb; O24602; -.
DR   PRIDE; O24602; -.
DR   GeneID; 100037781; -.
DR   KEGG; zma:100037781; -.
DR   MaizeGDB; 230283; -.
DR   eggNOG; ENOG502R4SP; Eukaryota.
DR   HOGENOM; CLU_1930598_0_0_1; -.
DR   OMA; WQTDEVA; -.
DR   OrthoDB; 1837526at2759; -.
DR   Proteomes; UP000007305; Chromosome 1.
DR   ExpressionAtlas; O24602; baseline.
DR   Genevisible; O24602; ZM.
DR   GO; GO:0048046; C:apoplast; ISS:UniProtKB.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
DR   GO; GO:0033612; F:receptor serine/threonine kinase binding; ISS:UniProtKB.
DR   GO; GO:0045168; P:cell-cell signaling involved in cell fate commitment; ISS:UniProtKB.
PE   1: Evidence at protein level;
KW   Developmental protein; Differentiation; Glycoprotein; Hydroxylation;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..131
FT                   /note="CLAVATA3/ESR (CLE)-related protein ESR1"
FT                   /id="PRO_0000401221"
FT   PEPTIDE         78..89
FT                   /note="ESR1p"
FT                   /evidence="ECO:0000250|UniProtKB:O49519"
FT                   /id="PRO_0000401222"
FT   REGION          49..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         81
FT                   /note="Hydroxyproline"
FT                   /evidence="ECO:0000250|UniProtKB:O49519"
FT   MOD_RES         84
FT                   /note="Hydroxyproline"
FT                   /evidence="ECO:0000250|UniProtKB:O49519"
FT   CARBOHYD        84
FT                   /note="O-linked (Ara...) hydroxyproline"
FT                   /evidence="ECO:0000250|UniProtKB:O49519"
SQ   SEQUENCE   131 AA;  14432 MW;  F4AE2AB9FB9FAA33 CRC64;
     MASRMGMVAI VSLFVCALAA STSVNANVWQ TDDIPVVNSN MVRHSNMERQ QQQGGFIGHR
     PRLASFNRAS NQDGDRKRTV PSGPDHMHHS IPSHTPQHPP VYVQALYEDD RSRTSSGPSK
     SIGPPPLSDR Y