ID   ESTE_HVAVE              Reviewed;         655 AA.
AC   A4KX74;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   23-FEB-2022, entry version 44.
DE   RecName: Full=Putative esterase;
DE            EC=3.1.1.1;
GN   ORFNames=ORF19;
OS   Heliothis virescens ascovirus 3e (HvAV-3e).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Ascoviridae; Ascovirus.
OX   NCBI_TaxID=260797;
OH   NCBI_TaxID=7100; Noctuidae (owlet moths).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17374755; DOI=10.1099/vir.0.82651-0;
RA   Asgari S., Davis J., Wood D., Wilson P., McGrath A.;
RT   "Sequence and organization of the Heliothis virescens ascovirus genome.";
RL   J. Gen. Virol. 88:1120-1132(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+);
CC         Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1;
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000305}.
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DR   EMBL; EF133465; ABO37205.1; -; Genomic_DNA.
DR   RefSeq; YP_001110871.1; NC_009233.1.
DR   SMR; A4KX74; -.
DR   GeneID; 5076189; -.
DR   KEGG; vg:5076189; -.
DR   Proteomes; UP000001324; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Hydrolase; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..655
FT                   /note="Putative esterase"
FT                   /id="PRO_0000330602"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        515
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   CARBOHYD        71
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        89
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        101
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        185
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        386
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        449
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        512
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        527
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        597
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   655 AA;  74351 MW;  A7735800A5AEEBEF CRC64;
     MCKSRLPTVL SLTLIYISIS IGFSVYFYVL MEAAYDQFSS MFESYTQTAV HLQSNSRTLK
     SDLSDYMQLL NYSRKFDESG EESVLRRHNI TTPRVFYIDL NYTTALGAEN RNLNMINFYA
     IPYRYVDLLD PFGNSIPVTG RTPATEYIDC SRDKKEKCID SIPPFDGVLD CLSLDIHMQP
     WSRNNKSFNR PIIIWLGEVA GELWRLVAGG LIVIRANYRR GCYGFLCHHD QSLPYRNQGV
     NDVLHAIDWT IENARHFAGD ISKITLAGHG ASASLVEYIR LNHGHHLPLD KYIVMSANNF
     GSRDLYCSSN SNVMVTTARL LGMPPSPATE SGKERSVYES VRYLSFVEPK LVMSKLYGLK
     AAFHPCPLSV NNRRASTFGI GFKTKNHTSS NCIRTANEQP VLFTNTLNEY HNFVYGSTVF
     THARSETILR TIGDMLSRHF IESRLAYANS STEKLIQQVN GQYNVVDGEF VDYDAFIRLL
     TDFAFIMPTV KMNEFTTECG GNSYHYVFDF GNSTHGDDLK MLTSSANDTS LTHFQRQLAD
     GLGFILSKFV RRGYPVKKQD GWCPSTGLVA QIMEMNTKDE NVVVKKSTEG VLIPLLNQSY
     VLHFHRVSVA KQKCYNRLGN VPFWNDLLKF HQSARRGWRD GDTGCARSKY LSEIV