ID   ESX2_STRA5              Reviewed;          96 AA.
AC   Q8DZR0;
DT   02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=ESAT-6-like protein SAG1039 {ECO:0000305};
GN   OrderedLocusNames=SAG1039;
OS   Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=208435;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-611 / 2603 V/R;
RX   PubMed=12200547; DOI=10.1073/pnas.182380799;
RA   Tettelin H., Masignani V., Cieslewicz M.J., Eisen J.A., Peterson S.N.,
RA   Wessels M.R., Paulsen I.T., Nelson K.E., Margarit I., Read T.D.,
RA   Madoff L.C., Wolf A.M., Beanan M.J., Brinkac L.M., Daugherty S.C.,
RA   DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Lewis M.R., Radune D.,
RA   Fedorova N.B., Scanlan D., Khouri H.M., Mulligan S., Carty H.A.,
RA   Cline R.T., Van Aken S.E., Gill J., Scarselli M., Mora M., Iacobini E.T.,
RA   Brettoni C., Galli G., Mariani M., Vegni F., Maione D., Rinaudo D.,
RA   Rappuoli R., Telford J.L., Kasper D.L., Grandi G., Fraser C.M.;
RT   "Complete genome sequence and comparative genomic analysis of an emerging
RT   human pathogen, serotype V Streptococcus agalactiae.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:12391-12396(2002).
RN   [2]
RP   X-RAY CRYSTALLOGRAPHY (1.30 ANGSTROMS) OF 3-96, AND SUBUNIT.
RC   STRAIN=ATCC BAA-611 / 2603 V/R;
RX   PubMed=24586681; DOI=10.1371/journal.pone.0089313;
RA   Poulsen C., Panjikar S., Holton S.J., Wilmanns M., Song Y.H.;
RT   "WXG100 protein superfamily consists of three subfamilies and exhibits an
RT   alpha-helical C-terminal conserved residue pattern.";
RL   PLoS ONE 9:E89313-E89313(2014).
CC   -!- SUBUNIT: Homodimer (PubMed:24586681). {ECO:0000269|PubMed:24586681}.
CC   -!- SIMILARITY: Belongs to the WXG100 family. sagEsxA-like subfamily.
CC       {ECO:0000305|PubMed:24586681}.
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DR   EMBL; AE009948; AAM99921.1; -; Genomic_DNA.
DR   RefSeq; NP_688049.1; NC_004116.1.
DR   RefSeq; WP_000057251.1; NC_004116.1.
DR   PDB; 3GVM; X-ray; 2.15 A; A/B/C/D=3-96.
DR   PDB; 3GWK; X-ray; 1.30 A; C/E=3-96.
DR   PDBsum; 3GVM; -.
DR   PDBsum; 3GWK; -.
DR   AlphaFoldDB; Q8DZR0; -.
DR   SMR; Q8DZR0; -.
DR   STRING; 208435.SAG1039; -.
DR   EnsemblBacteria; AAM99921; AAM99921; SAG1039.
DR   KEGG; sag:SAG1039; -.
DR   PATRIC; fig|208435.3.peg.1050; -.
DR   HOGENOM; CLU_158563_4_0_9; -.
DR   OMA; SDLKGMW; -.
DR   EvolutionaryTrace; Q8DZR0; -.
DR   Proteomes; UP000000821; Chromosome.
DR   InterPro; IPR036689; ESAT-6-like_sf.
DR   InterPro; IPR010310; T7SS_ESAT-6-like.
DR   Pfam; PF06013; WXG100; 1.
DR   SUPFAM; SSF140453; SSF140453; 1.
DR   TIGRFAMs; TIGR03930; WXG100_ESAT6; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome.
FT   CHAIN           1..96
FT                   /note="ESAT-6-like protein SAG1039"
FT                   /id="PRO_0000437935"
FT   HELIX           8..42
FT                   /evidence="ECO:0007829|PDB:3GWK"
FT   HELIX           49..93
FT                   /evidence="ECO:0007829|PDB:3GWK"
SQ   SEQUENCE   96 AA;  10690 MW;  4A2CC51F230850F2 CRC64;
     MAQIKLTPEE LRSSAQKYTA GSQQVTEVLN LLTQEQAVID ENWDGSTFDS FEAQFNELSP
     KITEFAQLLE DINQQLLKVA DIIEQTDADI ASQISG