ID   ESXB_CORDI              Reviewed;         105 AA.
AC   Q6NJ55;
DT   02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=ESAT-6-like protein EsxB {ECO:0000303|PubMed:19854905};
GN   Name=esxB {ECO:0000303|PubMed:19854905}; OrderedLocusNames=DIP0558;
OS   Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype
OS   gravis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=257309;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700971 / NCTC 13129 / Biotype gravis;
RX   PubMed=14602910; DOI=10.1093/nar/gkg874;
RA   Cerdeno-Tarraga A.-M., Efstratiou A., Dover L.G., Holden M.T.G.,
RA   Pallen M.J., Bentley S.D., Besra G.S., Churcher C.M., James K.D.,
RA   De Zoysa A., Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N.,
RA   Holroyd S., Jagels K., Moule S., Quail M.A., Rabbinowitsch E.,
RA   Rutherford K.M., Thomson N.R., Unwin L., Whitehead S., Barrell B.G.,
RA   Parkhill J.;
RT   "The complete genome sequence and analysis of Corynebacterium diphtheriae
RT   NCTC13129.";
RL   Nucleic Acids Res. 31:6516-6523(2003).
RN   [2]
RP   SUBUNIT.
RC   STRAIN=ATCC 700971 / NCTC 13129 / Biotype gravis;
RX   PubMed=19854905; DOI=10.1128/jb.01032-09;
RA   Callahan B., Nguyen K., Collins A., Valdes K., Caplow M., Crossman D.K.,
RA   Steyn A.J., Eisele L., Derbyshire K.M.;
RT   "Conservation of structure and protein-protein interactions mediated by the
RT   secreted mycobacterial proteins EsxA, EsxB, and EspA.";
RL   J. Bacteriol. 192:326-335(2010).
CC   -!- SUBUNIT: Forms a tight 1:1 complex with EsxB.
CC       {ECO:0000269|PubMed:19854905}.
CC   -!- MISCELLANEOUS: To improve expression in E.coli the proteins were cloned
CC       as a single protein in the order esxB-esxA with a cleavable thrombin
CC       tag (PubMed:19854905). {ECO:0000269|PubMed:19854905}.
CC   -!- SIMILARITY: Belongs to the WXG100 family. CFP-10 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; BX248355; CAE49070.1; -; Genomic_DNA.
DR   RefSeq; WP_010934381.1; NC_002935.2.
DR   AlphaFoldDB; Q6NJ55; -.
DR   SMR; Q6NJ55; -.
DR   STRING; 257309.DIP0558; -.
DR   EnsemblBacteria; CAE49070; CAE49070; DIP0558.
DR   GeneID; 47689939; -.
DR   KEGG; cdi:DIP0558; -.
DR   HOGENOM; CLU_151185_2_1_11; -.
DR   OMA; HSLMERW; -.
DR   OrthoDB; 1999616at2; -.
DR   Proteomes; UP000002198; Chromosome.
DR   InterPro; IPR036689; ESAT-6-like_sf.
DR   InterPro; IPR010310; T7SS_ESAT-6-like.
DR   Pfam; PF06013; WXG100; 1.
DR   SUPFAM; SSF140453; SSF140453; 1.
DR   TIGRFAMs; TIGR03930; WXG100_ESAT6; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..105
FT                   /note="ESAT-6-like protein EsxB"
FT                   /id="PRO_0000437937"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   105 AA;  11349 MW;  970A02418257FD9F CRC64;
     MSQGFKTEAD VMRNTAHRVD DTNQEVSAEL SRLRSIVDGV RASWEGTAQV SFDNLMQRWD
     ASAKGLQDAL QSISDNIRGN ATSFENVEAD NQSAFSAVGG QGLAL