ID   ESXC_MYCPA              Reviewed;          95 AA.
AC   Q9K548;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=ESAT-6-like protein EsxC {ECO:0000250|UniProtKB:P9WNI1};
DE   AltName: Full=ORF3890c;
GN   Name=esxC {ECO:0000250|UniProtKB:P9WNI1}; OrderedLocusNames=MAP_0161;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Bull T.J., Hermon-Taylor J., Pavlik I., El-Zaatari F., Tizard M.;
RT   "Study of IS900 loci in Mycobacterium avium subsp. paratuberculosis by
RT   multiplex PCR screening, shows homologous recombination around IS900
RT   insertions.";
RL   Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P9WNI1}.
CC       Note=Probably secreted via the ESX-2 / type VII secretion system
CC       (T7SS). {ECO:0000250|UniProtKB:P9WNI1}.
CC   -!- SIMILARITY: Belongs to the WXG100 family. ESAT-6 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AJ250015; CAB96047.1; -; Genomic_DNA.
DR   EMBL; AE016958; AAS02478.1; -; Genomic_DNA.
DR   RefSeq; WP_003876587.1; NC_002944.2.
DR   AlphaFoldDB; Q9K548; -.
DR   SMR; Q9K548; -.
DR   STRING; 262316.MAP_0161; -.
DR   EnsemblBacteria; AAS02478; AAS02478; MAP_0161.
DR   GeneID; 66691955; -.
DR   KEGG; mpa:MAP_0161; -.
DR   eggNOG; ENOG50329MM; Bacteria.
DR   HOGENOM; CLU_183730_0_0_11; -.
DR   OMA; AQLMEIH; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR036689; ESAT-6-like_sf.
DR   InterPro; IPR010310; T7SS_ESAT-6-like.
DR   Pfam; PF06013; WXG100; 1.
DR   SUPFAM; SSF140453; SSF140453; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Secreted.
FT   CHAIN           1..95
FT                   /note="ESAT-6-like protein EsxC"
FT                   /id="PRO_0000167817"
SQ   SEQUENCE   95 AA;  10110 MW;  2D3E3F434081C2EB CRC64;
     MSDPITYNPG AVADFATDVA SRAGQLQSIF DDTSNRTHAL QEFFAGHGAS GFFEAQAQML
     SGLQGLIDTI RQHGQTTSHV LDSAISTDQH IAGLF