ID   ESXC_MYCTO              Reviewed;          95 AA.
AC   P9WNI0; L0TE32; O05454;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=ESAT-6-like protein EsxC {ECO:0000250|UniProtKB:P9WNI1};
GN   Name=esxC {ECO:0000250|UniProtKB:P9WNI1}; OrderedLocusNames=MT4005;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P9WNI1}.
CC       Note=Probably secreted via the ESX-2 / type VII secretion system
CC       (T7SS). {ECO:0000250|UniProtKB:P9WNI1}.
CC   -!- SIMILARITY: Belongs to the WXG100 family. ESAT-6 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK48372.1; -; Genomic_DNA.
DR   PIR; C70598; C70598.
DR   RefSeq; WP_003899750.1; NZ_KK341228.1.
DR   AlphaFoldDB; P9WNI0; -.
DR   SMR; P9WNI0; -.
DR   EnsemblBacteria; AAK48372; AAK48372; MT4005.
DR   GeneID; 45427893; -.
DR   KEGG; mtc:MT4005; -.
DR   PATRIC; fig|83331.31.peg.4312; -.
DR   HOGENOM; CLU_183730_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR036689; ESAT-6-like_sf.
DR   InterPro; IPR010310; T7SS_ESAT-6-like.
DR   Pfam; PF06013; WXG100; 1.
DR   SUPFAM; SSF140453; SSF140453; 1.
PE   3: Inferred from homology;
KW   Secreted.
FT   CHAIN           1..95
FT                   /note="ESAT-6-like protein EsxC"
FT                   /id="PRO_0000427123"
SQ   SEQUENCE   95 AA;  9920 MW;  E554BBFAE55C56F5 CRC64;
     MSDQITYNPG AVSDFASDVG SRAGQLHMIY EDTASKTNAL QEFFAGHGAQ GFFDAQAQML
     SGLQGLIETV GQHGTTTGHV LDNAIGTDQA IAGLF