ID   ESXC_STAAC              Reviewed;         130 AA.
AC   Q5HJ85;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=ESAT-6 secretion system extracellular protein C {ECO:0000250|UniProtKB:P0C051};
DE            Short=Ess extracellular protein C {ECO:0000250|UniProtKB:P0C051};
GN   Name=esxC {ECO:0000250|UniProtKB:A0A0H2XIK2};
GN   Synonyms=esaC {ECO:0000250|UniProtKB:P0C051}; OrderedLocusNames=SACOL0277;
OS   Staphylococcus aureus (strain COL).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93062;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COL;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P0C051}.
CC       Note=Secreted via the ESAT-6 secretion system (Ess) / type VII
CC       secretion system (T7SS). {ECO:0000250|UniProtKB:P0C051}.
CC   -!- SIMILARITY: Belongs to the EsxC family. {ECO:0000305}.
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DR   EMBL; CP000046; AAW38831.1; -; Genomic_DNA.
DR   RefSeq; WP_001010289.1; NC_002951.2.
DR   AlphaFoldDB; Q5HJ85; -.
DR   SMR; Q5HJ85; -.
DR   EnsemblBacteria; AAW38831; AAW38831; SACOL0277.
DR   GeneID; 66838591; -.
DR   KEGG; sac:SACOL0277; -.
DR   HOGENOM; CLU_1936813_0_0_9; -.
DR   Proteomes; UP000000530; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Secreted; Virulence.
FT   CHAIN           1..130
FT                   /note="ESAT-6 secretion system extracellular protein C"
FT                   /id="PRO_0000087050"
SQ   SEQUENCE   130 AA;  14937 MW;  E4ADDB26B7706A8F CRC64;
     MNFNDIETMV KSKFKDIKKH AEEIAHEIEV RSGYLRKAEQ YKRLEFNLSF ALDDIESTAK
     DVQTAKSSAN KDSVTVKGKA PNTLYIEKRN LMKQKLEMLG EDIDKNKESL QKAKEIAGEK
     ASEYFNKAMN