ID   ESXI_MYCTO              Reviewed;          94 AA.
AC   P0DOA8; L0TEQ6; O08120; O08122; P96364; P9WNK0; Q9L781;
DT   07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT   07-SEP-2016, sequence version 1.
DT   25-MAY-2022, entry version 10.
DE   RecName: Full=ESAT-6-like protein EsxI {ECO:0000250|UniProtKB:P0DOA6};
GN   Name=esxI {ECO:0000250|UniProtKB:P0DOA6}; OrderedLocusNames=MT1066;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P0DOA6}.
CC       Note=Probably secreted via the ESX-5 / type VII secretion system
CC       (T7SS). {ECO:0000250|UniProtKB:P0DOA6}.
CC   -!- SIMILARITY: Belongs to the WXG100 family. ESAT-6 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK45317.1; -; Genomic_DNA.
DR   PIR; D70560; D70560.
DR   RefSeq; WP_003900722.1; NZ_KK341227.1.
DR   AlphaFoldDB; P0DOA8; -.
DR   SMR; P0DOA8; -.
DR   EnsemblBacteria; AAK45317; AAK45317; MT1066.
DR   KEGG; mtc:MT1066; -.
DR   HOGENOM; CLU_192559_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR009416; ESAT-6-like_Myco.
DR   InterPro; IPR036689; ESAT-6-like_sf.
DR   InterPro; IPR010310; T7SS_ESAT-6-like.
DR   Pfam; PF06013; WXG100; 1.
DR   PIRSF; PIRSF037656; DUF1066; 1.
DR   SUPFAM; SSF140453; SSF140453; 1.
PE   3: Inferred from homology;
KW   Secreted.
FT   CHAIN           1..94
FT                   /note="ESAT-6-like protein EsxI"
FT                   /id="PRO_0000427113"
SQ   SEQUENCE   94 AA;  9844 MW;  54341938BD93F645 CRC64;
     MTINYQFGDV DAHGAMIRAL AGLLEAEHQA IISDVLTASD FWGGAGSAAC QGFITQLGRN
     FQVIYEQANA HGQKVQAAGN NMAQTDSAVG SSWA