ID   ESXK_MYCBO              Reviewed;          98 AA.
AC   P0DOB1; A0A1R3XXM2; P59803; X2BGJ8;
DT   07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT   07-SEP-2016, sequence version 1.
DT   25-MAY-2022, entry version 20.
DE   RecName: Full=ESAT-6-like protein EsxK {ECO:0000250|UniProtKB:P9WNJ7};
GN   Name=esxK {ECO:0000250|UniProtKB:P9WNJ7}; OrderedLocusNames=BQ2027_MB1229;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBUNIT: Strongly interacts with EsxL to form a heterodimeric complex
CC       under reducing conditions. {ECO:0000250|UniProtKB:P9WNJ7}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P9WNJ7}.
CC       Note=Probably secreted via the ESX-5 / type VII secretion system
CC       (T7SS). {ECO:0000250|UniProtKB:P9WNJ7}.
CC   -!- SIMILARITY: Belongs to the WXG100 family. CFP-10 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; LT708304; SIT99830.1; -; Genomic_DNA.
DR   RefSeq; NP_854723.1; NC_002945.3.
DR   RefSeq; NP_854883.1; NC_002945.3.
DR   RefSeq; WP_003405345.1; NC_002945.4.
DR   AlphaFoldDB; P0DOB1; -.
DR   SMR; P0DOB1; -.
DR   EnsemblBacteria; SIT99830; SIT99830; BQ2027_MB1229.
DR   GeneID; 45425009; -.
DR   PATRIC; fig|233413.5.peg.1160; -.
DR   OMA; HAMRAMA; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR036689; ESAT-6-like_sf.
DR   InterPro; IPR010310; T7SS_ESAT-6-like.
DR   Pfam; PF06013; WXG100; 1.
DR   SUPFAM; SSF140453; SSF140453; 1.
DR   TIGRFAMs; TIGR03930; WXG100_ESAT6; 1.
PE   3: Inferred from homology;
KW   Secreted.
FT   CHAIN           1..98
FT                   /note="ESAT-6-like protein EsxK"
FT                   /id="PRO_0000436930"
SQ   SEQUENCE   98 AA;  10993 MW;  0ED04CBA64A779D1 CRC64;
     MASRFMTDPH AMRDMAGRFE VHAQTVEDEA RRMWASAQNI SGAGWSGMAE ATSLDTMTQM
     NQAFRNIVNM LHGVRDGLVR DANNYEQQEQ ASQQILSS