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ESXK_MYCTO
ID   ESXK_MYCTO              Reviewed;          98 AA.
AC   P9WNJ6; L0T8X9; O05299;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=ESAT-6-like protein EsxK {ECO:0000250|UniProtKB:P9WNJ7};
GN   Name=esxK {ECO:0000250|UniProtKB:P9WNJ7}; OrderedLocusNames=MT1235;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBUNIT: Strongly interacts with EsxL to form a heterodimeric complex
CC       under reducing conditions. {ECO:0000250|UniProtKB:P9WNJ7}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P9WNJ7}.
CC       Note=Probably secreted via the ESX-5 / type VII secretion system
CC       (T7SS). {ECO:0000250|UniProtKB:P9WNJ7}.
CC   -!- SIMILARITY: Belongs to the WXG100 family. CFP-10 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK45492.1; -; Genomic_DNA.
DR   PIR; C70608; C70608.
DR   RefSeq; WP_003900502.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WNJ6; -.
DR   SMR; P9WNJ6; -.
DR   EnsemblBacteria; AAK45492; AAK45492; MT1235.
DR   KEGG; mtc:MT1235; -.
DR   HOGENOM; CLU_171031_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR036689; ESAT-6-like_sf.
DR   InterPro; IPR010310; T7SS_ESAT-6-like.
DR   Pfam; PF06013; WXG100; 1.
DR   SUPFAM; SSF140453; SSF140453; 1.
DR   TIGRFAMs; TIGR03930; WXG100_ESAT6; 1.
PE   3: Inferred from homology;
KW   Secreted.
FT   CHAIN           1..98
FT                   /note="ESAT-6-like protein EsxK"
FT                   /id="PRO_0000427115"
SQ   SEQUENCE   98 AA;  10977 MW;  5AC41DEE70F269D6 CRC64;
     MATRFMTDPH AMRDMAGRFE VHAQTVEDEA RRMWASAQNI SGAGWSGMAE ATSLDTMAQM
     NQAFRNIVNM LHGVRDGLVR DANNYEQQEQ ASQQILSS
 
 
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