ID   ESXL_MYCTO              Reviewed;          94 AA.
AC   P9WNJ4; L0T8P7; O05300;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=ESAT-6-like protein EsxL {ECO:0000250|UniProtKB:P9WNJ5};
GN   Name=esxL {ECO:0000250|UniProtKB:P9WNJ5}; OrderedLocusNames=MT1236;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBUNIT: Strongly interacts with EsxK to form a heterodimeric complex
CC       under reducing conditions. {ECO:0000250|UniProtKB:P9WNJ5}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P9WNJ5}.
CC       Note=Probably secreted via the ESX-5 / type VII secretion system
CC       (T7SS). {ECO:0000250|UniProtKB:P9WNJ5}.
CC   -!- SIMILARITY: Belongs to the WXG100 family. ESAT-6 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK45493.1; -; Genomic_DNA.
DR   PIR; D70608; D70608.
DR   RefSeq; WP_003917414.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WNJ4; -.
DR   SMR; P9WNJ4; -.
DR   EnsemblBacteria; AAK45493; AAK45493; MT1236.
DR   KEGG; mtc:MT1236; -.
DR   PATRIC; fig|83331.31.peg.1335; -.
DR   HOGENOM; CLU_192559_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR009416; ESAT-6-like_Myco.
DR   InterPro; IPR036689; ESAT-6-like_sf.
DR   InterPro; IPR010310; T7SS_ESAT-6-like.
DR   Pfam; PF06013; WXG100; 1.
DR   PIRSF; PIRSF037656; DUF1066; 1.
DR   SUPFAM; SSF140453; SSF140453; 1.
PE   3: Inferred from homology;
KW   Secreted.
FT   CHAIN           1..94
FT                   /note="ESAT-6-like protein EsxL"
FT                   /id="PRO_0000427116"
SQ   SEQUENCE   94 AA;  9854 MW;  1182308F819DDB68 CRC64;
     MTINYQFGDV DAHGAMIRAQ AGLLEAEHQA IVRDVLAAGD FWGGAGSAAC QGFITQLGRN
     FQVIYEQANA HGQKVQAAGN NMAQTDSAVG SSWA